Ligand exchange of hemoglobin vesicle with the model device optimized its light response to gas-liquid boundary face more efficient

Daisuke Suzuki, Shinji Takeoka, Keitaro Sou, Eishun Tsuchida

Research output: Contribution to conferencePaper

Abstract

Phospholipid vesicle encapsulating concentrated human hemoglobin (Hb-vesicles) also known as liposomes is one of the candidates of oxygen carrier. In the manufacturing process, HbCO is converted to HbO 2, however it is inefficient because of the strong affinity of CO to Hb. We established a model device, that could convert HbCO to HbO 2in a liquid membrane. Using this device, we have achieve an efficient and contiguous conversion process of HbCO to HbO 2.

Original languageEnglish
Number of pages1
Publication statusPublished - 2005 Dec 1
Event54th SPSJ Symposium on Macromolecules - Yamagata, Japan
Duration: 2005 Sep 202005 Sep 22

Other

Other54th SPSJ Symposium on Macromolecules
CountryJapan
CityYamagata
Period05/9/2005/9/22

    Fingerprint

Keywords

  • Hemoglobin-vesicles
  • Ligand exchange
  • Liposome
  • Liquid membrane

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Suzuki, D., Takeoka, S., Sou, K., & Tsuchida, E. (2005). Ligand exchange of hemoglobin vesicle with the model device optimized its light response to gas-liquid boundary face more efficient. Paper presented at 54th SPSJ Symposium on Macromolecules, Yamagata, Japan.