Localization of glutamate-like immunoreactive neurons in the central and peripheral nervous system of the adult and developing pond snail, Lymnaea stagnalis

Dai Hatakeyama, Hitoshi Aonuma, Etsuro Ito, Károly Elekes

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

We investigated the distribution and projection patterns of central and peripheral glutamate-like immunoreactive (GLU-LIR) neurons in the adult and developing nervous system of Lymnaea. Altogether, 50-60 GLU-LIR neurons are present in the adult central nervous system. GLU-LIR labeling is shown in the interganglionic bundle system and at the varicosities in neuropil of the central ganglia. In the periphery, the foot, lip, and tentacle contain numerous GLU-LIR bipolar sensory neurons. In the juvenile Lymnaea, GLU-LIR elements at the periphery display a pattern of distribution similar to that seen in adults, whereas labeled neurons increase in number in the different ganglia of the central nervous system from juvenile stage P1 up to adulthood. During embryogenesis, GLU-LIR innervation can be detected first at the 50% stage of embryonic development (the E50% stage) in the neuropil of the cerebral and pedal ganglia, followed by the emergence of labeled pedal nerve roots at the E75% stage. Before hatching, at the E90% stage, a few GLU-LIR sensory cells can be found in the caudal foot region. Our findings indicate a wide range of occurrence and a broad role for glutamate in the gastropod nervous system; hence they provide a basis for future studies on glutamatergic events in networks underlying different behaviors.

Original languageEnglish
Pages (from-to)172-186
Number of pages15
JournalBiological Bulletin
Volume213
Issue number2
Publication statusPublished - 2007 Oct
Externally publishedYes

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Lymnaea
Lymnaea stagnalis
peripheral nervous system
Snails
Peripheral Nervous System
nervous system
glutamates
snail
central nervous system
snails
Glutamic Acid
Central Nervous System
pond
neurons
Neurons
Foot
Ganglia
Neuropil
embryonic development
gastropod

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Agricultural and Biological Sciences (miscellaneous)
  • Aquatic Science

Cite this

Localization of glutamate-like immunoreactive neurons in the central and peripheral nervous system of the adult and developing pond snail, Lymnaea stagnalis. / Hatakeyama, Dai; Aonuma, Hitoshi; Ito, Etsuro; Elekes, Károly.

In: Biological Bulletin, Vol. 213, No. 2, 10.2007, p. 172-186.

Research output: Contribution to journalArticle

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