Localization of serotonin transporter mRNA in the CNS of Lymnaea stagnalis

Hisayo Sadamoto, Z. Serfozo, E. Ito

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The serotonin transporter, SERT, is reported as a key molecule that regulates serotonergic neurotransmission. In the present study, we analyzed the localization of Lymnaea SERT (LymSERT) mRNA-containing neurons by in situ hybridization using frozen sections of the central nervous system (CNS) of Lymnaea. To precisely demonstrate the distribution of LymSERT mRNA-containing neurons, colocalization with serotonin immunoreactivity was also examined. The results showed that LymSERT mRNA was constitutively expressed and localized in the serotonin-containing neurons in the CNS.

Original languageEnglish
Pages (from-to)61-64
Number of pages4
JournalActa biologica Hungarica
Volume59
Issue numberSUPPL.
DOIs
Publication statusPublished - 2008 Jun 3
Externally publishedYes

Keywords

  • CNS
  • In situ hybridization
  • Lymnaea
  • Serotonin transporter

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)
  • Neurology

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