Location of the c-yes gene on the human chromosome and its expression in various tissues

Kentaro Senba, Yuji Yamanashi, Makoto Nishizawa, Jun Sukegawa, Michihiro Yoshida, Motomichi Sasaki, Tadashi Yamamoto, Kumao Toyoshima

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Analysis of DNA from human embryo fibroblasts showed that ten Eco RIfragments were hybridizable with the Yamaguchi sarcoma virus oncogene (vyes). Four of the Eco RI fragments were assigned to chromosome 18 and one to chromosome 6. There was evidence for multiple copies of yes-related genes in the human genome; however, only a single RNA species, 4.8 kilobases in length, was related to yes in various cells.

Original languageEnglish
Pages (from-to)1038-1040
Number of pages3
JournalScience
Volume227
Issue number4690
Publication statusPublished - 1985
Externally publishedYes

Fingerprint

Deoxyribonuclease EcoRI
Chromosomes, Human, Pair 18
Chromosomes, Human, Pair 6
Human Chromosomes
Human Genome
Oncogenes
Sarcoma
Embryonic Structures
Fibroblasts
RNA
Viruses
DNA
Genes

ASJC Scopus subject areas

  • General

Cite this

Senba, K., Yamanashi, Y., Nishizawa, M., Sukegawa, J., Yoshida, M., Sasaki, M., ... Toyoshima, K. (1985). Location of the c-yes gene on the human chromosome and its expression in various tissues. Science, 227(4690), 1038-1040.

Location of the c-yes gene on the human chromosome and its expression in various tissues. / Senba, Kentaro; Yamanashi, Yuji; Nishizawa, Makoto; Sukegawa, Jun; Yoshida, Michihiro; Sasaki, Motomichi; Yamamoto, Tadashi; Toyoshima, Kumao.

In: Science, Vol. 227, No. 4690, 1985, p. 1038-1040.

Research output: Contribution to journalArticle

Senba, K, Yamanashi, Y, Nishizawa, M, Sukegawa, J, Yoshida, M, Sasaki, M, Yamamoto, T & Toyoshima, K 1985, 'Location of the c-yes gene on the human chromosome and its expression in various tissues', Science, vol. 227, no. 4690, pp. 1038-1040.
Senba K, Yamanashi Y, Nishizawa M, Sukegawa J, Yoshida M, Sasaki M et al. Location of the c-yes gene on the human chromosome and its expression in various tissues. Science. 1985;227(4690):1038-1040.
Senba, Kentaro ; Yamanashi, Yuji ; Nishizawa, Makoto ; Sukegawa, Jun ; Yoshida, Michihiro ; Sasaki, Motomichi ; Yamamoto, Tadashi ; Toyoshima, Kumao. / Location of the c-yes gene on the human chromosome and its expression in various tissues. In: Science. 1985 ; Vol. 227, No. 4690. pp. 1038-1040.
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