Long-term potentiation in the optic tectum of rainbow trout

Masae Kinoshita, Toshiyuki Hosokawa, Akihisa Urano, Etsuro Ito

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

We examined synaptic plasticity in the optic tectum of rainbow trout by extracellular recordings. We found that the field-excitatory postsynaptic potential in the retinotectal synapses was potentiated by repetitive stimuli of 1.0 Hz for 20 s to the retinotectal afferents. The long-term potentiation (LTP) developed slowly, and was maintained for at least 2 h. Applications of an antagonist for N-methyl-d-aspartic acid (NMDA) receptors or Mg 2+-free saline showed that activation of NMDA receptors was required to form the LTP beyond the induction period. The present findings indicate that presynaptic stimulation in the retinotectal synapses causes LTP mediated by NMDA receptors in the optic tectum of rainbow trout.

Original languageEnglish
Pages (from-to)146-150
Number of pages5
JournalNeuroscience Letters
Volume370
Issue number2-3
DOIs
Publication statusPublished - 2004 Nov 11
Externally publishedYes

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Superior Colliculi
Long-Term Potentiation
Oncorhynchus mykiss
Synapses
Neuronal Plasticity
Excitatory Postsynaptic Potentials
aspartic acid receptor

Keywords

  • AMPA
  • Glutamate receptor
  • NMDA
  • Periventricular neuron
  • Teleost

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Long-term potentiation in the optic tectum of rainbow trout. / Kinoshita, Masae; Hosokawa, Toshiyuki; Urano, Akihisa; Ito, Etsuro.

In: Neuroscience Letters, Vol. 370, No. 2-3, 11.11.2004, p. 146-150.

Research output: Contribution to journalArticle

Kinoshita, Masae ; Hosokawa, Toshiyuki ; Urano, Akihisa ; Ito, Etsuro. / Long-term potentiation in the optic tectum of rainbow trout. In: Neuroscience Letters. 2004 ; Vol. 370, No. 2-3. pp. 146-150.
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