Lordosis in male rats: The facilitatory effect of mesencephalic dorsal raphe nucleus lesion

Masaki Kakeyama, Korehito Yamanouchi

    Research output: Contribution to journalArticle

    21 Citations (Scopus)

    Abstract

    The dorsal raphe nucleus was destroyed (DRL) by a radiofrequency lesion generator in castrated male rats, and lordosis behavior was observed. Five weeks after the surgery, all animals were implanted with two Silastic tubes containing estradiol (E2). Behavioral tests were started 2 days after implantation of E2 and carried out every other day for 16 days. Castrated control and sham-operated control males showed low incidence of lordosis and low lordosis quotient (LQ) throughout the tests, whereas all the DRL males displayed lordosis and the mean LQ of the group was significantly higher than that of control groups, but lower than that of an ovariectomized female group. These results suggest that the dorsal raphe nucleus plays an important role in inhibiting lordosis in male rat brain.

    Original languageEnglish
    Pages (from-to)181-184
    Number of pages4
    JournalPhysiology and Behavior
    Volume51
    Issue number1
    DOIs
    Publication statusPublished - 1992

    Fingerprint

    Lordosis
    Dorsal Raphe Nucleus
    Estradiol
    Control Groups
    Incidence
    Brain

    Keywords

    • Dorsal raphe nucleus
    • Inhibitory system
    • Lesions
    • Lordosis behavior
    • Male rat
    • Midbrain

    ASJC Scopus subject areas

    • Physiology (medical)
    • Behavioral Neuroscience

    Cite this

    Lordosis in male rats : The facilitatory effect of mesencephalic dorsal raphe nucleus lesion. / Kakeyama, Masaki; Yamanouchi, Korehito.

    In: Physiology and Behavior, Vol. 51, No. 1, 1992, p. 181-184.

    Research output: Contribution to journalArticle

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