Abstract
The dorsal raphe nucleus was destroyed (DRL) by a radiofrequency lesion generator in castrated male rats, and lordosis behavior was observed. Five weeks after the surgery, all animals were implanted with two Silastic tubes containing estradiol (E2). Behavioral tests were started 2 days after implantation of E2 and carried out every other day for 16 days. Castrated control and sham-operated control males showed low incidence of lordosis and low lordosis quotient (LQ) throughout the tests, whereas all the DRL males displayed lordosis and the mean LQ of the group was significantly higher than that of control groups, but lower than that of an ovariectomized female group. These results suggest that the dorsal raphe nucleus plays an important role in inhibiting lordosis in male rat brain.
| Original language | English |
|---|---|
| Pages (from-to) | 181-184 |
| Number of pages | 4 |
| Journal | Physiology and Behavior |
| Volume | 51 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1992 |
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Keywords
- Dorsal raphe nucleus
- Inhibitory system
- Lesions
- Lordosis behavior
- Male rat
- Midbrain
ASJC Scopus subject areas
- Physiology (medical)
- Behavioral Neuroscience
Cite this
Lordosis in male rats : The facilitatory effect of mesencephalic dorsal raphe nucleus lesion. / Kakeyama, Masaki; Yamanouchi, Korehito.
In: Physiology and Behavior, Vol. 51, No. 1, 1992, p. 181-184.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Lordosis in male rats
T2 - The facilitatory effect of mesencephalic dorsal raphe nucleus lesion
AU - Kakeyama, Masaki
AU - Yamanouchi, Korehito
PY - 1992
Y1 - 1992
N2 - The dorsal raphe nucleus was destroyed (DRL) by a radiofrequency lesion generator in castrated male rats, and lordosis behavior was observed. Five weeks after the surgery, all animals were implanted with two Silastic tubes containing estradiol (E2). Behavioral tests were started 2 days after implantation of E2 and carried out every other day for 16 days. Castrated control and sham-operated control males showed low incidence of lordosis and low lordosis quotient (LQ) throughout the tests, whereas all the DRL males displayed lordosis and the mean LQ of the group was significantly higher than that of control groups, but lower than that of an ovariectomized female group. These results suggest that the dorsal raphe nucleus plays an important role in inhibiting lordosis in male rat brain.
AB - The dorsal raphe nucleus was destroyed (DRL) by a radiofrequency lesion generator in castrated male rats, and lordosis behavior was observed. Five weeks after the surgery, all animals were implanted with two Silastic tubes containing estradiol (E2). Behavioral tests were started 2 days after implantation of E2 and carried out every other day for 16 days. Castrated control and sham-operated control males showed low incidence of lordosis and low lordosis quotient (LQ) throughout the tests, whereas all the DRL males displayed lordosis and the mean LQ of the group was significantly higher than that of control groups, but lower than that of an ovariectomized female group. These results suggest that the dorsal raphe nucleus plays an important role in inhibiting lordosis in male rat brain.
KW - Dorsal raphe nucleus
KW - Inhibitory system
KW - Lesions
KW - Lordosis behavior
KW - Male rat
KW - Midbrain
UR - http://www.scopus.com/inward/record.url?scp=0026593404&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026593404&partnerID=8YFLogxK
U2 - 10.1016/0031-9384(92)90221-M
DO - 10.1016/0031-9384(92)90221-M
M3 - Article
VL - 51
SP - 181
EP - 184
JO - Physiology and Behavior
JF - Physiology and Behavior
SN - 0031-9384
IS - 1
ER -