TY - JOUR
T1 - Low-dose Gamma Knife radiosurgery for cavernous sinus hemangioma
T2 - Report of 3 cases and literature review
AU - Ivanov, P.
AU - Chernov, M.
AU - Hayashi, M.
AU - Nakaya, K.
AU - Izawa, M.
AU - Murata, N.
AU - Kubo, O.
AU - Ujiie, H.
AU - Muragaki, Y.
AU - Nakamura, R.
AU - Iseki, H.
AU - Hori, T.
AU - Takakura, K.
PY - 2008/6
Y1 - 2008/6
N2 - Optimal management of cavernous sinus heman-giomas remains unclear. Total microsurgical removal of these neoplasms may be extremely difficult due to their rich vascularization. Three cases of cavernous sinus hemangioma treated with low-dose Gamma Knife radiosurgery are presented. Marginal dose varied from 10 to 13 Gy. Treatment planning and radiation dosimetry were done with a goal of conformal and selective coverage of the lesion with 50% prescription isodose line using multiisocenter technique. In all cases significant shrinkage of the neoplasm was marked at 3 months after treatment. Mean volume reduction at 12 months after radiosurgery was 60% (range: 45-75%). In all patients the shrinkage of the neoplasm was accompanied by notable improvement of the preexistent oculomotor nerve palsy. No radiosurgery-related complications were met during follow-up. In conclusion, low-dose Gamma Knife radiosurgery seems to be very effective for management of cavernous sinus hemangiomas, and can be considered as a treatment modality of choice for these lesions.
AB - Optimal management of cavernous sinus heman-giomas remains unclear. Total microsurgical removal of these neoplasms may be extremely difficult due to their rich vascularization. Three cases of cavernous sinus hemangioma treated with low-dose Gamma Knife radiosurgery are presented. Marginal dose varied from 10 to 13 Gy. Treatment planning and radiation dosimetry were done with a goal of conformal and selective coverage of the lesion with 50% prescription isodose line using multiisocenter technique. In all cases significant shrinkage of the neoplasm was marked at 3 months after treatment. Mean volume reduction at 12 months after radiosurgery was 60% (range: 45-75%). In all patients the shrinkage of the neoplasm was accompanied by notable improvement of the preexistent oculomotor nerve palsy. No radiosurgery-related complications were met during follow-up. In conclusion, low-dose Gamma Knife radiosurgery seems to be very effective for management of cavernous sinus hemangiomas, and can be considered as a treatment modality of choice for these lesions.
KW - Cavernous sinus hemangioma
KW - Gamma knife radiosurgery
KW - Treatment
UR - http://www.scopus.com/inward/record.url?scp=46849087201&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=46849087201&partnerID=8YFLogxK
U2 - 10.1055/s-2008-1065346
DO - 10.1055/s-2008-1065346
M3 - Article
C2 - 18521784
AN - SCOPUS:46849087201
SN - 0946-7211
VL - 51
SP - 140
EP - 146
JO - Minimally Invasive Neurosurgery
JF - Minimally Invasive Neurosurgery
IS - 3
ER -