TY - JOUR
T1 - Low-volume exercise training and vitamin E supplementation attenuates oxidative stress in postmenopausal women
AU - Takahashi, Masaki
AU - Miyashita, Masashi
AU - Park, Jong Hwan
AU - Kawanishi, Noriaki
AU - Bae, Seong Ryu
AU - Nakamura, Yoshio
AU - Sakamoto, Shizuo
AU - Suzuki, Katsuhiko
PY - 2013
Y1 - 2013
N2 - The purpose of this study was to investigate the effects of low-volume exercise training (90 min/wk) and vitamin E supplementation on oxidative stress markers in postmenopausal women. The participants were non-randomly assigned the following four groups: control (C, n=8), vitamin E (S, n=8), exercise (Ex, n=6), or vitamin E and exercise (S+Ex, n=7). The S and S+Ex groups were instructed to take vitamin E (α-tocopherol, 300 mg/d) capsules for 12 wk. The exercise program of Ex and S+Ex groups consisted of walking for a 30-60 min/session 2 d per week for 12 wk. The serum derivatives of reactive oxygen metabolites concentrations were significantly decreased in the Ex, and S+Ex groups after 12 wk compared with the baseline values (three-factor ANOVA, an interaction between exercise and time, p<0.05). Conversely, serum biological antioxidant potential concentrations in the S and Ex groups were significantly higher at 12 wk than at the baseline, but not in the S+Ex group (three-factor ANOVA, an interaction between supplementation, exercise and time, p<0.05). Plasma thioredoxin concentrations in the S, Ex, and S+Ex groups were significantly higher at 12 wk than at the baseline values (three-factor ANOVA, interactions between exercise and time, and between supplementation, exercise and time, p<0.05). Our findings suggest that low-volume physical activity may improve resting oxidative stress status in postmenopausal women.
AB - The purpose of this study was to investigate the effects of low-volume exercise training (90 min/wk) and vitamin E supplementation on oxidative stress markers in postmenopausal women. The participants were non-randomly assigned the following four groups: control (C, n=8), vitamin E (S, n=8), exercise (Ex, n=6), or vitamin E and exercise (S+Ex, n=7). The S and S+Ex groups were instructed to take vitamin E (α-tocopherol, 300 mg/d) capsules for 12 wk. The exercise program of Ex and S+Ex groups consisted of walking for a 30-60 min/session 2 d per week for 12 wk. The serum derivatives of reactive oxygen metabolites concentrations were significantly decreased in the Ex, and S+Ex groups after 12 wk compared with the baseline values (three-factor ANOVA, an interaction between exercise and time, p<0.05). Conversely, serum biological antioxidant potential concentrations in the S and Ex groups were significantly higher at 12 wk than at the baseline, but not in the S+Ex group (three-factor ANOVA, an interaction between supplementation, exercise and time, p<0.05). Plasma thioredoxin concentrations in the S, Ex, and S+Ex groups were significantly higher at 12 wk than at the baseline values (three-factor ANOVA, interactions between exercise and time, and between supplementation, exercise and time, p<0.05). Our findings suggest that low-volume physical activity may improve resting oxidative stress status in postmenopausal women.
KW - Aging
KW - Atherosclerosis
KW - Oxidative stress
KW - Physical activity
KW - α-tocopherol
UR - http://www.scopus.com/inward/record.url?scp=84892533348&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84892533348&partnerID=8YFLogxK
U2 - 10.3177/jnsv.59.375
DO - 10.3177/jnsv.59.375
M3 - Article
C2 - 24418871
AN - SCOPUS:84892533348
SN - 0301-4800
VL - 59
SP - 375
EP - 383
JO - The Journal of vitaminology
JF - The Journal of vitaminology
IS - 5
ER -