Medical image-based analysis of flow in heart with congenital heart disease: Numerical simulation of intraventricular flow

Lijun Chen, Jinlong Liu, Haifa Hong, Aimin Sun, Jinfen Liu, Yuqi Zhang, Mitsuo Umezu

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    Quantitatively analyze the characteristics of intraventricular flow is critical for the diagnosis of congenital heart disease (CHD). Although several techniques are applied in clinic currently, the information which they provided is not satisfied with the requirement of the therapies of CHD. Here, we introduced the method of computational fluid dynamics (CFD) to investigate the intraventricular hemodynamics using a reconstructed model of left ventricle (LV) based on cardiac magnetic resonance (CMR) images. A large, counterclockwise, vortex was observed. It persisted in the periods of slow filling phase and atrial contraction phase in diastole. A smaller vortex was found around the outflow tract. An annular vortex is formed in the base region downstream of the mitral orifice. The vortices vanished quickly at the end-diastole. These results indicate the technique of CFD is a promising tool which can be used to evaluate the hemodynamics in LV. Understanding the characteristics of intraventricular flow is helpful for the improvement of CHD.

    Original languageEnglish
    Title of host publication2015 10th Asian Control Conference: Emerging Control Techniques for a Sustainable World, ASCC 2015
    PublisherInstitute of Electrical and Electronics Engineers Inc.
    ISBN (Print)9781479978625
    DOIs
    Publication statusPublished - 2015 Sep 8
    Event10th Asian Control Conference, ASCC 2015 - Kota Kinabalu, Malaysia
    Duration: 2015 May 312015 Jun 3

    Other

    Other10th Asian Control Conference, ASCC 2015
    CountryMalaysia
    CityKota Kinabalu
    Period15/5/3115/6/3

    Keywords

    • computational fluid dynamics
    • congenital heart disease
    • hemodynamics
    • intraventricular flow
    • left ventricle

    ASJC Scopus subject areas

    • Control and Systems Engineering

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  • Cite this

    Chen, L., Liu, J., Hong, H., Sun, A., Liu, J., Zhang, Y., & Umezu, M. (2015). Medical image-based analysis of flow in heart with congenital heart disease: Numerical simulation of intraventricular flow. In 2015 10th Asian Control Conference: Emerging Control Techniques for a Sustainable World, ASCC 2015 [7244764] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ASCC.2015.7244764