Method for estimating the temperature distribution associated with the vessel cooling effect in radio frequency ablation

Xiaowei Lu, Hayato Kikuchi, Kazumasa Hirooka, Yosuke Isobe, Hiroki Watanabe, Yo Kobayashi, Tomoyuki Miyashita, Masakatsu G. Fujie

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Recently, radio frequency ablation (RFA) has become one of the most popular thermal treatments for liver cancer. RFA is minimally invasive and effective in inducing tumor coagulation, however, because use the procedure depends on the experience of the physician, consistent accuracy cannot be guaranteed. In particular, when the tumor is close to a large vessel, a suboptimal ablation margin can result in tumor recurrence. To improve the accuracy of RFA treatment, we have developed an RFA supporting system, which was constructed by using finite element method and operated by means of a model-based control method. In this study, we focused on the cooling effect of flow volume inside a large vessel during RFA, and analyzed heat transfer between the large vessel and liver tissue using a model. We derived the heat transfer parameter (the Nusselt number (Nu)) between the large vessel and liver tissue during RFA by using a finite-element method (FEM). When the Nu for FEM analysis had a value of 3, the FEM analysis model was representative of the actual ablation objective, and the maximum error between FEM analysis and the measurement results was within 2.0[°C]. Thus, it was suggested that the Nu was effective for FEM analysis regarding heat transfer between a large vessel and tissue. However, according to the differences between the results of FEM analysis and measurements concerning the three livers, the heat transfer volume was determined by the Nu, which is different individually in common with other thermal properties. In conclusion, it is necessary to consider the individual differences in the heat transfer volume parameter for FEM analysis.

Original languageEnglish
Title of host publication2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages4836-4839
Number of pages4
ISBN (Electronic)9781424492718
DOIs
Publication statusPublished - 2015 Nov 4
Event37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy
Duration: 2015 Aug 252015 Aug 29

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume2015-November
ISSN (Print)1557-170X

Other

Other37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
Country/TerritoryItaly
CityMilan
Period15/8/2515/8/29

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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