Microbial circadian oscillatory systems in Neurospora and Synechococcus: Models for cellular clocks

Hideo Iwasaki, J. C Jay C Dunlap

Research output: Contribution to journalArticle

74 Citations (Scopus)


Common regulatory patterns have emerged among the feedback loops lying within circadian systems. Significant progress in dissecting the mechanism of clock resetting by temperature and the role of the WC proteins in the Neurospora light response has accompanied documentation of the importance of nuclear localization and phosphorylation-induced turnover of FRQ to this circadian cycle. The long-awaited molecular description of a transcription/translation loop in the Synechococcus circadian system represents a quantal step forward, followed by the identification of additional important proteins and interactions. Finally, the adaptive significance of rhythms in Synechococcus and by extension in all clocks nicely ties up an extraordinary year.

Original languageEnglish
Pages (from-to)189-196
Number of pages8
JournalCurrent Opinion in Microbiology
Issue number2
Publication statusPublished - 2000 Apr 1
Externally publishedYes


ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology

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