Microfluidic sedimentation system for separation of plasma from whole blood

Chiaki Kuroda; Yoshimichi Ohki; Hiroki Ashiba; Makoto Fujimaki; Koichi Awazu; Torahiko Tanaka; Makoto Makishima

doi:10.1109/ICSENS.2014.6985389

Microfluidic sedimentation system for separation of plasma from whole blood

Chiaki Kuroda, Yoshimichi Ohki, Hiroki Ashiba, Makoto Fujimaki, Koichi Awazu^*, Torahiko Tanaka, Makoto Makishima

^*Corresponding author for this work

Kagami Memorial Research Institute for Materials Science and Technology

Research output: Contribution to journal › Conference article › peer-review

7 Citations (Scopus)

Abstract

A microfluidic system for a portable and speedy blood test device has been developed. In the system, blood is injected into a cylindrical channel with a diameter of 3.0 mm and a height of 3.0 mm from the bottom to the top. When the blood ascends the channel, blood cells sediment at the bottom and plasma is separated at the top. This system can be manufactured easily at a low cost by simply bonding two identical polydimethylsiloxane chips. Pure plasma can be obtained successfully from a very tiny amount of blood, less than a drop (9 μL).

Original language	English
Article number	6985389
Pages (from-to)	1854-1857
Number of pages	4
Journal	Proceedings of IEEE Sensors
Volume	2014-December
Issue number	December
DOIs	https://doi.org/10.1109/ICSENS.2014.6985389
Publication status	Published - 2014 Dec 12
Event	13th IEEE SENSORS Conference, SENSORS 2014 - Valencia, Spain Duration: 2014 Nov 2 → 2014 Nov 5

Keywords

Blood
Microfluidics
Plasma extraction
Sedimentation

ASJC Scopus subject areas

Electrical and Electronic Engineering

Access to Document

10.1109/ICSENS.2014.6985389

Cite this

@article{41a85d77d41e4db79a9e060acdc16df6,

title = "Microfluidic sedimentation system for separation of plasma from whole blood",

abstract = "A microfluidic system for a portable and speedy blood test device has been developed. In the system, blood is injected into a cylindrical channel with a diameter of 3.0 mm and a height of 3.0 mm from the bottom to the top. When the blood ascends the channel, blood cells sediment at the bottom and plasma is separated at the top. This system can be manufactured easily at a low cost by simply bonding two identical polydimethylsiloxane chips. Pure plasma can be obtained successfully from a very tiny amount of blood, less than a drop (9 μL).",

keywords = "Blood, Microfluidics, Plasma extraction, Sedimentation",

author = "Chiaki Kuroda and Yoshimichi Ohki and Hiroki Ashiba and Makoto Fujimaki and Koichi Awazu and Torahiko Tanaka and Makoto Makishima",

note = "Publisher Copyright: {\textcopyright} 2014 IEEE.; 13th IEEE SENSORS Conference, SENSORS 2014 ; Conference date: 02-11-2014 Through 05-11-2014",

year = "2014",

month = dec,

day = "12",

doi = "10.1109/ICSENS.2014.6985389",

language = "English",

volume = "2014-December",

pages = "1854--1857",

journal = "Proceedings of IEEE Sensors",

issn = "1930-0395",

number = "December",

}

TY - JOUR

T1 - Microfluidic sedimentation system for separation of plasma from whole blood

AU - Kuroda, Chiaki

AU - Ohki, Yoshimichi

AU - Ashiba, Hiroki

AU - Fujimaki, Makoto

AU - Awazu, Koichi

AU - Tanaka, Torahiko

AU - Makishima, Makoto

PY - 2014/12/12

Y1 - 2014/12/12

N2 - A microfluidic system for a portable and speedy blood test device has been developed. In the system, blood is injected into a cylindrical channel with a diameter of 3.0 mm and a height of 3.0 mm from the bottom to the top. When the blood ascends the channel, blood cells sediment at the bottom and plasma is separated at the top. This system can be manufactured easily at a low cost by simply bonding two identical polydimethylsiloxane chips. Pure plasma can be obtained successfully from a very tiny amount of blood, less than a drop (9 μL).

AB - A microfluidic system for a portable and speedy blood test device has been developed. In the system, blood is injected into a cylindrical channel with a diameter of 3.0 mm and a height of 3.0 mm from the bottom to the top. When the blood ascends the channel, blood cells sediment at the bottom and plasma is separated at the top. This system can be manufactured easily at a low cost by simply bonding two identical polydimethylsiloxane chips. Pure plasma can be obtained successfully from a very tiny amount of blood, less than a drop (9 μL).

KW - Blood

KW - Microfluidics

KW - Plasma extraction

KW - Sedimentation

UR - http://www.scopus.com/inward/record.url?scp=84931044590&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84931044590&partnerID=8YFLogxK

U2 - 10.1109/ICSENS.2014.6985389

DO - 10.1109/ICSENS.2014.6985389

M3 - Conference article

AN - SCOPUS:84931044590

VL - 2014-December

SP - 1854

EP - 1857

JO - Proceedings of IEEE Sensors

JF - Proceedings of IEEE Sensors

SN - 1930-0395

IS - December

M1 - 6985389

T2 - 13th IEEE SENSORS Conference, SENSORS 2014

Y2 - 2 November 2014 through 5 November 2014

ER -

Microfluidic sedimentation system for separation of plasma from whole blood

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this