Microwave atomic force microscope: MG63 osteoblast-like cells analysis on nanometer scale

Lan Zhang, Yuanhui Song, Atsushi Hosoi, Yasuyuki Morita, Yang Ju

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper, we report a non-invasive and nondestructive probing method for analyzing the MG63 osteoblast-like cells. High-frequency Microwave atomic force microscope (M-AFM) can sense the topography and microwave image of MG63 cells simultaneously in one scanning process. Under the frequency modulation (FM) AFM mode, this powerful instrument is applied successfully to create a microwave image of MG63 cells with nanometer-scale spatial resolution. By analyzing the results, quantification such as, the number and distribution of organelles and proteins of MG63 cells as well as their dimension and electrical property information can be characterized.

Original languageEnglish
Title of host publicationDTIP 2014 - Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Print)9782355000287
DOIs
Publication statusPublished - 2014 Mar 9
Externally publishedYes
Event2014 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS, DTIP 2014 - Cannes, France
Duration: 2014 Apr 22014 Apr 4

Other

Other2014 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS, DTIP 2014
CountryFrance
CityCannes
Period14/4/214/4/4

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Keywords

  • AFM
  • MG63 cell
  • Microwave
  • Non-contact

ASJC Scopus subject areas

  • Computer Graphics and Computer-Aided Design
  • Computer Science Applications
  • Hardware and Architecture

Cite this

Zhang, L., Song, Y., Hosoi, A., Morita, Y., & Ju, Y. (2014). Microwave atomic force microscope: MG63 osteoblast-like cells analysis on nanometer scale. In DTIP 2014 - Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS [7056644] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/DTIP.2014.7056644