Microwave atomic force microscope: MG63 osteoblast-like cells analysis on nanometer scale

Lan Zhang; Yuanhui Song; Atsushi Hosoi; Yasuyuki Morita; Yang Ju

doi:10.1109/DTIP.2014.7056644

Microwave atomic force microscope: MG63 osteoblast-like cells analysis on nanometer scale

Lan Zhang, Yuanhui Song, Atsushi Hosoi, Yasuyuki Morita, Yang Ju^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

In this paper, we report a non-invasive and nondestructive probing method for analyzing the MG63 osteoblast-like cells. High-frequency Microwave atomic force microscope (M-AFM) can sense the topography and microwave image of MG63 cells simultaneously in one scanning process. Under the frequency modulation (FM) AFM mode, this powerful instrument is applied successfully to create a microwave image of MG63 cells with nanometer-scale spatial resolution. By analyzing the results, quantification such as, the number and distribution of organelles and proteins of MG63 cells as well as their dimension and electrical property information can be characterized.

Original language	English
Title of host publication	DTIP 2014 - Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Print)	9782355000287
DOIs	https://doi.org/10.1109/DTIP.2014.7056644
Publication status	Published - 2014 Mar 9
Externally published	Yes
Event	2014 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS, DTIP 2014 - Cannes, France Duration: 2014 Apr 2 → 2014 Apr 4

Other

Other	2014 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS, DTIP 2014
Country/Territory	France
City	Cannes
Period	14/4/2 → 14/4/4

Keywords

AFM
MG63 cell
Microwave
Non-contact

ASJC Scopus subject areas

Computer Graphics and Computer-Aided Design
Computer Science Applications
Hardware and Architecture

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10.1109/DTIP.2014.7056644

Cite this

Microwave atomic force microscope : MG63 osteoblast-like cells analysis on nanometer scale. / Zhang, Lan; Song, Yuanhui; Hosoi, Atsushi et al.

DTIP 2014 - Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS. Institute of Electrical and Electronics Engineers Inc., 2014. 7056644.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Zhang, L, Song, Y, Hosoi, A, Morita, Y & Ju, Y 2014, Microwave atomic force microscope: MG63 osteoblast-like cells analysis on nanometer scale. in DTIP 2014 - Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS., 7056644, Institute of Electrical and Electronics Engineers Inc., 2014 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS, DTIP 2014, Cannes, France, 14/4/2. https://doi.org/10.1109/DTIP.2014.7056644

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title = "Microwave atomic force microscope: MG63 osteoblast-like cells analysis on nanometer scale",

abstract = "In this paper, we report a non-invasive and nondestructive probing method for analyzing the MG63 osteoblast-like cells. High-frequency Microwave atomic force microscope (M-AFM) can sense the topography and microwave image of MG63 cells simultaneously in one scanning process. Under the frequency modulation (FM) AFM mode, this powerful instrument is applied successfully to create a microwave image of MG63 cells with nanometer-scale spatial resolution. By analyzing the results, quantification such as, the number and distribution of organelles and proteins of MG63 cells as well as their dimension and electrical property information can be characterized.",

keywords = "AFM, MG63 cell, Microwave, Non-contact",

author = "Lan Zhang and Yuanhui Song and Atsushi Hosoi and Yasuyuki Morita and Yang Ju",

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doi = "10.1109/DTIP.2014.7056644",

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booktitle = "DTIP 2014 - Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS",

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T2 - 2014 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS, DTIP 2014

AU - Zhang, Lan

AU - Song, Yuanhui

AU - Hosoi, Atsushi

AU - Morita, Yasuyuki

AU - Ju, Yang

PY - 2014/3/9

Y1 - 2014/3/9

N2 - In this paper, we report a non-invasive and nondestructive probing method for analyzing the MG63 osteoblast-like cells. High-frequency Microwave atomic force microscope (M-AFM) can sense the topography and microwave image of MG63 cells simultaneously in one scanning process. Under the frequency modulation (FM) AFM mode, this powerful instrument is applied successfully to create a microwave image of MG63 cells with nanometer-scale spatial resolution. By analyzing the results, quantification such as, the number and distribution of organelles and proteins of MG63 cells as well as their dimension and electrical property information can be characterized.

AB - In this paper, we report a non-invasive and nondestructive probing method for analyzing the MG63 osteoblast-like cells. High-frequency Microwave atomic force microscope (M-AFM) can sense the topography and microwave image of MG63 cells simultaneously in one scanning process. Under the frequency modulation (FM) AFM mode, this powerful instrument is applied successfully to create a microwave image of MG63 cells with nanometer-scale spatial resolution. By analyzing the results, quantification such as, the number and distribution of organelles and proteins of MG63 cells as well as their dimension and electrical property information can be characterized.

KW - AFM

KW - MG63 cell

KW - Microwave

KW - Non-contact

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M3 - Conference contribution

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SN - 9782355000287

BT - DTIP 2014 - Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS

PB - Institute of Electrical and Electronics Engineers Inc.

Y2 - 2 April 2014 through 4 April 2014

ER -

Microwave atomic force microscope: MG63 osteoblast-like cells analysis on nanometer scale

Abstract

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Keywords

ASJC Scopus subject areas

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