Modeling of lung's electrical impedance using fractional calculus for analysis of heat generation during RF-ablation

Nozomu Yamazaki, Yo Kobayashi, Hayato Kikuchi, Yosuke Isobe, Xiaowei Lu, Tomoyuki Miyashita, Masakatsu G. Fujie

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    1 Citation (Scopus)

    Abstract

    Recently, Radio Frequency Ablation (RFA) is becoming a popular therapy for various cancers such as liver, breast, or lung cancer. RFA is one kinds of thermal therapy. However, it has been often reported about excessive ablation or non-ablation due to difficult control of ablation energy. In order to solve these difficulties, we have been proposed robotized RF-ablation system for precise cancer treatment. We have been tried to control heat energy by control of electromagnetic-wave frequency. In this paper, we reported about relation among electrical impedance of lung, lung's internal air volumes, and heat energy by use of electromagnetic-wave. In case of RFA for lung cancer, heat energy depends on electrical impedance and lung's internal air volumes. Electrical impedance has the dependence of electromagnetic-wave frequency and the dependence of lung's internal air volumes. Therefore, firstly we considered about fractional calculus model between lung's internal air volumes and electrical impedance. Secondly, we measured electric impedance frequency characteristic of lung with change of lung's internal air volumes. The measured and modeled results showed that use of fractional calculus realized high accurate model for electrical impedance of lung. And, from the results of numerical analysis of heat energy, it is supposed that control of electromagnetic-wave frequency has a small effectiveness for lung tissue ablation even if lung includes abundant air.

    Original languageEnglish
    Title of host publication2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
    PublisherInstitute of Electrical and Electronics Engineers Inc.
    Pages5323-5328
    Number of pages6
    ISBN (Print)9781424479290
    DOIs
    Publication statusPublished - 2014 Nov 2
    Event2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 - Chicago, United States
    Duration: 2014 Aug 262014 Aug 30

    Other

    Other2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
    CountryUnited States
    CityChicago
    Period14/8/2614/8/30

    ASJC Scopus subject areas

    • Health Informatics
    • Computer Science Applications
    • Biomedical Engineering

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  • Cite this

    Yamazaki, N., Kobayashi, Y., Kikuchi, H., Isobe, Y., Lu, X., Miyashita, T., & Fujie, M. G. (2014). Modeling of lung's electrical impedance using fractional calculus for analysis of heat generation during RF-ablation. In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 (pp. 5323-5328). [6944828] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2014.6944828