Molecular cloning of newt sex pheromone precursor cDNAs: Evidence for the existence of species-specific forms of pheromones

T. Iwata; K. Umezawa; F. Toyoda; N. Takahashi; H. Matsukawa; K. Yamamoto; S. Miura; H. Hayashi; S. Kikuyama

doi:10.1016/S0014-5793(99)01062-5

Molecular cloning of newt sex pheromone precursor cDNAs: Evidence for the existence of species-specific forms of pheromones

T. Iwata, K. Umezawa, F. Toyoda, N. Takahashi, H. Matsukawa, K. Yamamoto, S. Miura, H. Hayashi, S. Kikuyama^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

Cloning of cDNA encoding a decapeptide pheromone (sodefrin) that attracts conspecific female newts was attempted. A cDNA clone encoding a protein consisting of 189 amino acid residues including a sodefrin sequence was isolated from a Cynops pyrrhogaster abdominal gland cDNA library. Likewise, a cDNA clone encoding a molecule comparable to the sodefrin precursor was obtained from a Cynops ensicauda abdominal gland cDNA library. This clone encoded a precursor protein of 192 amino acid residues, including a sodefrin-like peptide sequence with substitutions of two amino acid residues. This is the first report of a peptide pheromone precursor in vertebrates. Copyright (C) 1999 Federation of European Biochemical Societies.

Original language	English
Pages (from-to)	400-404
Number of pages	5
Journal	FEBS Letters
Volume	457
Issue number	3
DOIs	https://doi.org/10.1016/S0014-5793(99)01062-5
Publication status	Published - 1999 Sept 3

Keywords

cDNA cloning
Female newt attracting pheromone
Pheromone precursor protein
Sodefrin

ASJC Scopus subject areas

Biochemistry
Biophysics
Molecular Biology

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10.1016/S0014-5793(99)01062-5

Cite this

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title = "Molecular cloning of newt sex pheromone precursor cDNAs: Evidence for the existence of species-specific forms of pheromones",

abstract = "Cloning of cDNA encoding a decapeptide pheromone (sodefrin) that attracts conspecific female newts was attempted. A cDNA clone encoding a protein consisting of 189 amino acid residues including a sodefrin sequence was isolated from a Cynops pyrrhogaster abdominal gland cDNA library. Likewise, a cDNA clone encoding a molecule comparable to the sodefrin precursor was obtained from a Cynops ensicauda abdominal gland cDNA library. This clone encoded a precursor protein of 192 amino acid residues, including a sodefrin-like peptide sequence with substitutions of two amino acid residues. This is the first report of a peptide pheromone precursor in vertebrates. Copyright (C) 1999 Federation of European Biochemical Societies.",

keywords = "cDNA cloning, Female newt attracting pheromone, Pheromone precursor protein, Sodefrin",

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T2 - Evidence for the existence of species-specific forms of pheromones

AU - Iwata, T.

AU - Umezawa, K.

AU - Toyoda, F.

AU - Takahashi, N.

AU - Matsukawa, H.

AU - Yamamoto, K.

AU - Miura, S.

AU - Hayashi, H.

AU - Kikuyama, S.

PY - 1999/9/3

Y1 - 1999/9/3

N2 - Cloning of cDNA encoding a decapeptide pheromone (sodefrin) that attracts conspecific female newts was attempted. A cDNA clone encoding a protein consisting of 189 amino acid residues including a sodefrin sequence was isolated from a Cynops pyrrhogaster abdominal gland cDNA library. Likewise, a cDNA clone encoding a molecule comparable to the sodefrin precursor was obtained from a Cynops ensicauda abdominal gland cDNA library. This clone encoded a precursor protein of 192 amino acid residues, including a sodefrin-like peptide sequence with substitutions of two amino acid residues. This is the first report of a peptide pheromone precursor in vertebrates. Copyright (C) 1999 Federation of European Biochemical Societies.

AB - Cloning of cDNA encoding a decapeptide pheromone (sodefrin) that attracts conspecific female newts was attempted. A cDNA clone encoding a protein consisting of 189 amino acid residues including a sodefrin sequence was isolated from a Cynops pyrrhogaster abdominal gland cDNA library. Likewise, a cDNA clone encoding a molecule comparable to the sodefrin precursor was obtained from a Cynops ensicauda abdominal gland cDNA library. This clone encoded a precursor protein of 192 amino acid residues, including a sodefrin-like peptide sequence with substitutions of two amino acid residues. This is the first report of a peptide pheromone precursor in vertebrates. Copyright (C) 1999 Federation of European Biochemical Societies.

KW - cDNA cloning

KW - Female newt attracting pheromone

KW - Pheromone precursor protein

KW - Sodefrin

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Molecular cloning of newt sex pheromone precursor cDNAs: Evidence for the existence of species-specific forms of pheromones

Abstract

Keywords

ASJC Scopus subject areas

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