Molecularly designed nanoparticles by dispersion of self-assembled organosiloxane-based mesophases

Shigeru Sakamoto, Yasuhiro Tamura, Hideo Hata, Yasuhiro Sakamoto, Atsushi Shimojima, Kazuyuki Kuroda

    Research output: Contribution to journalArticle

    4 Citations (Scopus)

    Abstract

    The design of siloxane-based nanoparticles is important for many applications. Here we show a novel approach to form core-shell silica nanoparticles of a few nanometers in size through the principle of "dispersion of ordered mesostructures into single nanocomponents". Self-assembled siloxane-organic hybrids derived from amphiphilic alkyl-oligosiloxanes were postsynthetically dispersed in organic solvent to yield uniform nanoparticles consisting of dense lipophilic shells and hydrophilic siloxane cores. Insitu encapsulation of fluorescent dyes into the nanoparticles demonstrated their ability to function as nanocarriers. Self-assembled hybrid nanoparticles: A new type of oligosiloxane precursor self-assembles into reverse-micellar mesostructures, which can be transformed to nanoparticles with a siloxane core and an organic shell by dispersion in nonpolar organic solvents.

    Original languageEnglish
    Pages (from-to)9173-9177
    Number of pages5
    JournalAngewandte Chemie - International Edition
    Volume53
    Issue number35
    DOIs
    Publication statusPublished - 2014 Aug 25

    Fingerprint

    Siloxanes
    Nanoparticles
    Organic solvents
    Fluorescent Dyes
    Encapsulation
    Silicon Dioxide
    Dyes
    Silica

    Keywords

    • amphiphiles
    • inorganic-organic hybrids
    • nanoparticles
    • organosiloxanes
    • self-assembly

    ASJC Scopus subject areas

    • Chemistry(all)
    • Catalysis

    Cite this

    Molecularly designed nanoparticles by dispersion of self-assembled organosiloxane-based mesophases. / Sakamoto, Shigeru; Tamura, Yasuhiro; Hata, Hideo; Sakamoto, Yasuhiro; Shimojima, Atsushi; Kuroda, Kazuyuki.

    In: Angewandte Chemie - International Edition, Vol. 53, No. 35, 25.08.2014, p. 9173-9177.

    Research output: Contribution to journalArticle

    Sakamoto, Shigeru ; Tamura, Yasuhiro ; Hata, Hideo ; Sakamoto, Yasuhiro ; Shimojima, Atsushi ; Kuroda, Kazuyuki. / Molecularly designed nanoparticles by dispersion of self-assembled organosiloxane-based mesophases. In: Angewandte Chemie - International Edition. 2014 ; Vol. 53, No. 35. pp. 9173-9177.
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