Multilevel modeling of physiological systems and simulation platform: Physiodesigner, flint and flint K3 service

Yoshiyuki Asai*, Takeshi Abe, Masao Okita, Tomohiro Okuyama, Nobukazu Yoshioka, Shigetsohi Yokoyama, Masaru Nagaku, Ken Ichi Hagihara, Hiroaki Kitano

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

13 Citations (Scopus)

Abstract

Software framework to support modeling and performing simulations of multilevel physiological systems has been developed and expanded to support the cloud computing. The framework is composed of two blocks, i.e. PhysioDesigner and Flint. PhysioDesigner is an application providing a graphical user interface for assisting users in multilevel modeling of physiological functions and a terminal interface for script-based model building. Models built on PhysioDesigner are written in PHML (the physiological hierarchy markup language). Flint is a standalone simulator, supporting MPI for parallel computing on a proper system environment. Based on the standalone application, Flint K3 system supporting cloud computing has been developed, which provides a solution for portable high performance simulation. At the website of Flint K3, users can upload models described in PHML. In addition, PhysioDesigner and other applications can submit simulation jobs to Flint K3 directly at online.

Original languageEnglish
Title of host publicationProceedings - 2012 IEEE/IPSJ 12th International Symposium on Applications and the Internet, SAINT 2012
Pages215-219
Number of pages5
DOIs
Publication statusPublished - 2012
Externally publishedYes
Event2012 IEEE/IPSJ 12th International Symposium on Applications and the Internet, SAINT 2012 - Izmir, Turkey
Duration: 2012 Jul 162012 Jul 20

Publication series

NameProceedings - 2012 IEEE/IPSJ 12th International Symposium on Applications and the Internet, SAINT 2012

Conference

Conference2012 IEEE/IPSJ 12th International Symposium on Applications and the Internet, SAINT 2012
Country/TerritoryTurkey
CityIzmir
Period12/7/1612/7/20

Keywords

  • cloud computing
  • integrated physiology
  • multilevel modeling
  • systems biology

ASJC Scopus subject areas

  • Computer Networks and Communications

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