Multinuclear catalyst for copper-catalyzed asymmetric conjugate addition of organozinc reagents

Kohei Endo, Mika Ogawa, Takanori Shibata

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    62 Citations (Scopus)

    Abstract

    (Figure Presented) A whole lot o' metal: An efficient copper-catalyzed asymmetric conjugate addition was achieved using a binol-derived ligand. The catalytic system has a turnover number of 2000, and the excellent cata-lytic performance could be attributed to the generation of a multinuclear complex such as 1. binol = 2, 2'-dihydroxy-l, 1'-binaphthyl.

    Original languageEnglish
    Pages (from-to)2410-2413
    Number of pages4
    JournalAngewandte Chemie - International Edition
    Volume49
    Issue number13
    Publication statusPublished - 2010 Mar 22

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    Keywords

    • Alkylation
    • Copper
    • Michael addition
    • Synthetic methods
    • Zinc

    ASJC Scopus subject areas

    • Chemistry(all)
    • Catalysis
    • Medicine(all)

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