Multinuclear Cu-catalysts based on SPINOL-PHOS in asymmetric conjugate addition of organozinc reagents

Kohei Endo, Daisuke Hamada, Sayuri Yakeishi, Mika Ogawa, Takanori Shibata

    Research output: Contribution to journalArticle

    29 Citations (Scopus)

    Abstract

    Multinuclear Cu/Zn complex-catalyzed efficient asymmetric conjugate addition of organozinc reagents to acyclic and cyclic enones has been developed in the presence of a wide variety of regioisomeric chiral diols bearing phosphorus moieties as ligands. The regioisomeric SPINOL-PHOS ligands based on a SPINOL architecture showed an unexpected inversion of stereoselectivity.

    Original languageEnglish
    Pages (from-to)2342-2345
    Number of pages4
    JournalOrganic Letters
    Volume14
    Issue number9
    DOIs
    Publication statusPublished - 2012 May 4

    Fingerprint

    reagents
    Bearings (structural)
    Ligands
    catalysts
    Stereoselectivity
    ligands
    Catalysts
    Phosphorus
    phosphorus
    inversions

    ASJC Scopus subject areas

    • Organic Chemistry
    • Physical and Theoretical Chemistry
    • Biochemistry

    Cite this

    Multinuclear Cu-catalysts based on SPINOL-PHOS in asymmetric conjugate addition of organozinc reagents. / Endo, Kohei; Hamada, Daisuke; Yakeishi, Sayuri; Ogawa, Mika; Shibata, Takanori.

    In: Organic Letters, Vol. 14, No. 9, 04.05.2012, p. 2342-2345.

    Research output: Contribution to journalArticle

    Endo, Kohei ; Hamada, Daisuke ; Yakeishi, Sayuri ; Ogawa, Mika ; Shibata, Takanori. / Multinuclear Cu-catalysts based on SPINOL-PHOS in asymmetric conjugate addition of organozinc reagents. In: Organic Letters. 2012 ; Vol. 14, No. 9. pp. 2342-2345.
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    AU - Ogawa, Mika

    AU - Shibata, Takanori

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