Multinuclear Cu-catalysts based on SPINOL-PHOS in asymmetric conjugate addition of organozinc reagents

Kohei Endo, Daisuke Hamada, Sayuri Yakeishi, Mika Ogawa, Takanori Shibata

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

Multinuclear Cu/Zn complex-catalyzed efficient asymmetric conjugate addition of organozinc reagents to acyclic and cyclic enones has been developed in the presence of a wide variety of regioisomeric chiral diols bearing phosphorus moieties as ligands. The regioisomeric SPINOL-PHOS ligands based on a SPINOL architecture showed an unexpected inversion of stereoselectivity.

Original languageEnglish
Pages (from-to)2342-2345
Number of pages4
JournalOrganic Letters
Volume14
Issue number9
DOIs
Publication statusPublished - 2012 May 4

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Multinuclear Cu-catalysts based on SPINOL-PHOS in asymmetric conjugate addition of organozinc reagents'. Together they form a unique fingerprint.

Cite this