Muscle oxygen dynamics during cycling exercise in angina pectoris patients

Shun Takagi, Norio Murase, Ryotaro Kime, Masatsugu Niwayama, Takuya Osada, Toshihito Katsumura

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Muscle O2 dynamics during ramp cycling exercise were compared between angina pectoris patients (AP; n = 7, age: 73 ± 6 years) after coronary artery bypass grafting and age-, height-, and body weight-matched elderly control subjects (CON; n = 7, age: 74 ± 8 years). Muscle O2 saturation (SmO2) and relative change in deoxygenated (Δdeoxy-Hb) and total hemoglobin concentration (Δtotal-Hb) were measured continuously during exercise in the vastus lateralis (VL) by near infrared spatial resolved spectroscopy. Pulmonary O2 uptake (VO2) was also monitored throughout exercise to determine peak VO2. In AP, SmO2 was significantly higher, and Δdeoxy-Hb was significantly lower during exercise, compared to CON. In all subjects, ΔSmO2 (values at peak exercise minus values at resting) was negatively correlated to peak VO2 (r = −0.52, p < 0.05), and Δdeoxy-Hb at peak exercise tended to be negatively associated with peak VO2 (r = 0.48, p = 0.07). Blunted skeletal muscle deoxygenation response was observed in AP patients, which may be related to lower aerobic capacity in AP patients.

Original languageEnglish
Title of host publicationOxygen Transport to Tissue XXXVIII
PublisherSpringer New York LLC
Pages291-297
Number of pages7
Volume923
ISBN (Print)9783319388083
DOIs
Publication statusPublished - 2016
Event43rd Annual Meeting of the International Society on Oxygen Transport to Tissue, ISOTT 2015 - Wuhan, China
Duration: 2015 Jul 112015 Jul 16

Publication series

NameAdvances in Experimental Medicine and Biology
Volume923
ISSN (Print)00652598
ISSN (Electronic)22148019

Other

Other43rd Annual Meeting of the International Society on Oxygen Transport to Tissue, ISOTT 2015
CountryChina
CityWuhan
Period15/7/1115/7/16

Fingerprint

Angina Pectoris
Muscle
Exercise
Oxygen
Muscles
Hemoglobins
Spectroscopy
Infrared radiation
Architectural Accessibility
Quadriceps Muscle
Coronary Artery Bypass
Spectrum Analysis
Skeletal Muscle
Body Weight
Lung

Keywords

  • Aerobic capacity
  • Blood volume
  • Ischemic heart disease
  • Muscle oxygen saturation
  • Near infrared spectroscopy

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Takagi, S., Murase, N., Kime, R., Niwayama, M., Osada, T., & Katsumura, T. (2016). Muscle oxygen dynamics during cycling exercise in angina pectoris patients. In Oxygen Transport to Tissue XXXVIII (Vol. 923, pp. 291-297). (Advances in Experimental Medicine and Biology; Vol. 923). Springer New York LLC. https://doi.org/10.1007/978-3-319-38810-6_39

Muscle oxygen dynamics during cycling exercise in angina pectoris patients. / Takagi, Shun; Murase, Norio; Kime, Ryotaro; Niwayama, Masatsugu; Osada, Takuya; Katsumura, Toshihito.

Oxygen Transport to Tissue XXXVIII. Vol. 923 Springer New York LLC, 2016. p. 291-297 (Advances in Experimental Medicine and Biology; Vol. 923).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Takagi, S, Murase, N, Kime, R, Niwayama, M, Osada, T & Katsumura, T 2016, Muscle oxygen dynamics during cycling exercise in angina pectoris patients. in Oxygen Transport to Tissue XXXVIII. vol. 923, Advances in Experimental Medicine and Biology, vol. 923, Springer New York LLC, pp. 291-297, 43rd Annual Meeting of the International Society on Oxygen Transport to Tissue, ISOTT 2015, Wuhan, China, 15/7/11. https://doi.org/10.1007/978-3-319-38810-6_39
Takagi S, Murase N, Kime R, Niwayama M, Osada T, Katsumura T. Muscle oxygen dynamics during cycling exercise in angina pectoris patients. In Oxygen Transport to Tissue XXXVIII. Vol. 923. Springer New York LLC. 2016. p. 291-297. (Advances in Experimental Medicine and Biology). https://doi.org/10.1007/978-3-319-38810-6_39
Takagi, Shun ; Murase, Norio ; Kime, Ryotaro ; Niwayama, Masatsugu ; Osada, Takuya ; Katsumura, Toshihito. / Muscle oxygen dynamics during cycling exercise in angina pectoris patients. Oxygen Transport to Tissue XXXVIII. Vol. 923 Springer New York LLC, 2016. pp. 291-297 (Advances in Experimental Medicine and Biology).
@inproceedings{a7785a99a3254837b7d8f6dd86358882,
title = "Muscle oxygen dynamics during cycling exercise in angina pectoris patients",
abstract = "Muscle O2 dynamics during ramp cycling exercise were compared between angina pectoris patients (AP; n = 7, age: 73 ± 6 years) after coronary artery bypass grafting and age-, height-, and body weight-matched elderly control subjects (CON; n = 7, age: 74 ± 8 years). Muscle O2 saturation (SmO2) and relative change in deoxygenated (Δdeoxy-Hb) and total hemoglobin concentration (Δtotal-Hb) were measured continuously during exercise in the vastus lateralis (VL) by near infrared spatial resolved spectroscopy. Pulmonary O2 uptake (VO2) was also monitored throughout exercise to determine peak VO2. In AP, SmO2 was significantly higher, and Δdeoxy-Hb was significantly lower during exercise, compared to CON. In all subjects, ΔSmO2 (values at peak exercise minus values at resting) was negatively correlated to peak VO2 (r = −0.52, p < 0.05), and Δdeoxy-Hb at peak exercise tended to be negatively associated with peak VO2 (r = 0.48, p = 0.07). Blunted skeletal muscle deoxygenation response was observed in AP patients, which may be related to lower aerobic capacity in AP patients.",
keywords = "Aerobic capacity, Blood volume, Ischemic heart disease, Muscle oxygen saturation, Near infrared spectroscopy",
author = "Shun Takagi and Norio Murase and Ryotaro Kime and Masatsugu Niwayama and Takuya Osada and Toshihito Katsumura",
year = "2016",
doi = "10.1007/978-3-319-38810-6_39",
language = "English",
isbn = "9783319388083",
volume = "923",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer New York LLC",
pages = "291--297",
booktitle = "Oxygen Transport to Tissue XXXVIII",

}

TY - GEN

T1 - Muscle oxygen dynamics during cycling exercise in angina pectoris patients

AU - Takagi, Shun

AU - Murase, Norio

AU - Kime, Ryotaro

AU - Niwayama, Masatsugu

AU - Osada, Takuya

AU - Katsumura, Toshihito

PY - 2016

Y1 - 2016

N2 - Muscle O2 dynamics during ramp cycling exercise were compared between angina pectoris patients (AP; n = 7, age: 73 ± 6 years) after coronary artery bypass grafting and age-, height-, and body weight-matched elderly control subjects (CON; n = 7, age: 74 ± 8 years). Muscle O2 saturation (SmO2) and relative change in deoxygenated (Δdeoxy-Hb) and total hemoglobin concentration (Δtotal-Hb) were measured continuously during exercise in the vastus lateralis (VL) by near infrared spatial resolved spectroscopy. Pulmonary O2 uptake (VO2) was also monitored throughout exercise to determine peak VO2. In AP, SmO2 was significantly higher, and Δdeoxy-Hb was significantly lower during exercise, compared to CON. In all subjects, ΔSmO2 (values at peak exercise minus values at resting) was negatively correlated to peak VO2 (r = −0.52, p < 0.05), and Δdeoxy-Hb at peak exercise tended to be negatively associated with peak VO2 (r = 0.48, p = 0.07). Blunted skeletal muscle deoxygenation response was observed in AP patients, which may be related to lower aerobic capacity in AP patients.

AB - Muscle O2 dynamics during ramp cycling exercise were compared between angina pectoris patients (AP; n = 7, age: 73 ± 6 years) after coronary artery bypass grafting and age-, height-, and body weight-matched elderly control subjects (CON; n = 7, age: 74 ± 8 years). Muscle O2 saturation (SmO2) and relative change in deoxygenated (Δdeoxy-Hb) and total hemoglobin concentration (Δtotal-Hb) were measured continuously during exercise in the vastus lateralis (VL) by near infrared spatial resolved spectroscopy. Pulmonary O2 uptake (VO2) was also monitored throughout exercise to determine peak VO2. In AP, SmO2 was significantly higher, and Δdeoxy-Hb was significantly lower during exercise, compared to CON. In all subjects, ΔSmO2 (values at peak exercise minus values at resting) was negatively correlated to peak VO2 (r = −0.52, p < 0.05), and Δdeoxy-Hb at peak exercise tended to be negatively associated with peak VO2 (r = 0.48, p = 0.07). Blunted skeletal muscle deoxygenation response was observed in AP patients, which may be related to lower aerobic capacity in AP patients.

KW - Aerobic capacity

KW - Blood volume

KW - Ischemic heart disease

KW - Muscle oxygen saturation

KW - Near infrared spectroscopy

UR - http://www.scopus.com/inward/record.url?scp=84984815313&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84984815313&partnerID=8YFLogxK

U2 - 10.1007/978-3-319-38810-6_39

DO - 10.1007/978-3-319-38810-6_39

M3 - Conference contribution

SN - 9783319388083

VL - 923

T3 - Advances in Experimental Medicine and Biology

SP - 291

EP - 297

BT - Oxygen Transport to Tissue XXXVIII

PB - Springer New York LLC

ER -