Nazumamide A, a thrombin-inhibitory Tetrapeptide, from a marine sponge, theonella sp.

Nobuhiro Fusetani, Youichi Nakao, Shigeki Matsunaga

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Nazumamide A, a thrombin-inhibiting linear @Tetrapeptide, was isolated from a marine sponge, Theonella sp. The structure of nazumamide A was determined by interpretation of 2D NMR data and by chemical degradation as 2,5-dihydroxybenzoyl-l-arginyl-l-prolyl-l-isoleucyl-l-α-aminobutyric acid.

Original languageEnglish
Pages (from-to)7073-7074
Number of pages2
JournalTetrahedron Letters
Volume32
Issue number48
DOIs
Publication statusPublished - 1991 Nov 25
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Nazumamide A, a thrombin-inhibitory Tetrapeptide, from a marine sponge, theonella sp.'. Together they form a unique fingerprint.

  • Cite this