Nazumamide A, a thrombin-inhibitory Tetrapeptide, from a marine sponge, theonella sp.

Nobuhiro Fusetani, Youichi Nakao, Shigeki Matsunaga

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Nazumamide A, a thrombin-inhibiting linear @Tetrapeptide, was isolated from a marine sponge, Theonella sp. The structure of nazumamide A was determined by interpretation of 2D NMR data and by chemical degradation as 2,5-dihydroxybenzoyl-l-arginyl-l-prolyl-l-isoleucyl-l-α-aminobutyric acid.

Original languageEnglish
Pages (from-to)7073-7074
Number of pages2
JournalTetrahedron Letters
Volume32
Issue number48
DOIs
Publication statusPublished - 1991 Nov 25
Externally publishedYes

Fingerprint

Theonella
Porifera
Thrombin
Aminobutyrates
Nuclear magnetic resonance
Degradation
nazumamide A

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Nazumamide A, a thrombin-inhibitory Tetrapeptide, from a marine sponge, theonella sp. / Fusetani, Nobuhiro; Nakao, Youichi; Matsunaga, Shigeki.

In: Tetrahedron Letters, Vol. 32, No. 48, 25.11.1991, p. 7073-7074.

Research output: Contribution to journalArticle

Fusetani, Nobuhiro ; Nakao, Youichi ; Matsunaga, Shigeki. / Nazumamide A, a thrombin-inhibitory Tetrapeptide, from a marine sponge, theonella sp. In: Tetrahedron Letters. 1991 ; Vol. 32, No. 48. pp. 7073-7074.
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