Near-infrared hyperspectral imaging system for detection of polypoidal choroidal vasculopathy

Daisuke Muramatsu, Yasuyuki Yamauchi, Tsuyoshi Agawa, Maki Mishima, Setsuko Kawakami, Hiroshi Goto, Amano Yu, Katsuhiro Nakano, Shunsuke Tanaka, Atsushi Nakamura, Takayuki Sota

Research output: Contribution to journalArticlepeer-review


Purpose: To describe and report a non-invasive imaging system for the detection of polypoidal choroidal vasculopathy (PCV). Objects and Method: This study was made on 11 eyes of 11 cases of PCV The series comprised 8 males and 3 females. The age averaged 71 years. A fundus camera was modified and installed with a near-infrared hyperspectral imager. A false color image was constructed based on reflection spectra and relative reflection spectra. The finding was compared with indocyanine green (ICG) angiogram. Results: Area of PCV showed lower spectral reflection. Relative reflection also decreased when longer wavelength was used. The obtained images matched with the areas of PCV of ICG angiogram. Conclusion: Our near-infrared hyperspectral imaging system promises to be of value in the detection of PCV.

Original languageEnglish
Pages (from-to)443-448
Number of pages6
JournalJapanese Journal of Clinical Ophthalmology
Issue number4
Publication statusPublished - 2012 Apr 15
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology

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