Near-infrared hyperspectral imaging system for detection of polypoidal choroidal vasculopathy

Daisuke Muramatsu*, Yasuyuki Yamauchi, Tsuyoshi Agawa, Maki Mishima, Setsuko Kawakami, Hiroshi Goto, Amano Yu, Katsuhiro Nakano, Shunsuke Tanaka, Atsushi Nakamura, Takayuki Sota

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Purpose: To describe and report a non-invasive imaging system for the detection of polypoidal choroidal vasculopathy (PCV). Objects and Method: This study was made on 11 eyes of 11 cases of PCV The series comprised 8 males and 3 females. The age averaged 71 years. A fundus camera was modified and installed with a near-infrared hyperspectral imager. A false color image was constructed based on reflection spectra and relative reflection spectra. The finding was compared with indocyanine green (ICG) angiogram. Results: Area of PCV showed lower spectral reflection. Relative reflection also decreased when longer wavelength was used. The obtained images matched with the areas of PCV of ICG angiogram. Conclusion: Our near-infrared hyperspectral imaging system promises to be of value in the detection of PCV.

Original languageEnglish
Pages (from-to)443-448
Number of pages6
JournalJapanese Journal of Clinical Ophthalmology
Issue number4
Publication statusPublished - 2012 Apr 15
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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