Neuroendocrine modulation of stress response in the anuran, Rana esculenta

Gilberto Mosconi, Francesco Palermo, Marcello Carotti, Sakae Kikuyama, Kazutoshi Yamamoto, Alberta M. Polzonetti-Magni

    Research output: Contribution to journalArticle

    14 Citations (Scopus)

    Abstract

    In amphibians, as in other vertebrates, stress stimuli have been found to affect different functions, including development, growth, and reproduction. A wide range of responsiveness to stressors has been reported for amphibians; for instance, capture and/or captivity stress induced changes both in the hypothalamus-pituitary-interrenal and hypothalamus-pituitary-gonadal axes. However, few studies have examined the response to stress in terms of recovery and/or adaptation by applying stress paradigms for a short and long-term duration. In the present paper, the short-term captivity stress responses were evaluated in the anuran Rana esculenta by measuring peripheral corticosterone, androgens, prolactin (PRL), and growth hormone (GH) changes. Moreover, in long-term captivity and salinity stress, effects were evaluated by measuring peripheral PRL changes and those of PRL mRNA in the pituitary together with plasma corticosterone and androgens. Short-term (24 h) captivity stress induced an increase of peripheral corticosterone together with that of GH and PRL since these hormones are involved in the "alarm phase" and in energy demand of stressed animals. The opposite trend was found for peripheral androgens, in view of the negative effects exerted by stress in the reproductive axis. In long-term (1 month) captivity and salinity stress, responses were consistent with the increasing of PRL mRNA at pituitary level, through a long-loop feed-back mechanism depending on the decreasing levels of peripheral PRL, whereas no changes were found in the levels of plasma corticosterone and androgens. Therefore, it seems that Rana esculenta activates different neuroendocrine mechanisms depending on the duration of stress and on the types of stressors.

    Original languageEnglish
    Pages (from-to)401-408
    Number of pages8
    JournalAmphibia Reptilia
    Volume27
    Issue number3
    DOIs
    Publication statusPublished - 2006 Aug

    Fingerprint

    Rana esculenta
    prolactin
    stress response
    corticosterone
    androgens
    captivity
    androgen
    hypothalamus
    somatotropin
    hormone
    salt stress
    amphibians
    amphibian
    duration
    plasma
    salinity
    growth and development
    feedback mechanism
    vertebrates
    hormones

    ASJC Scopus subject areas

    • Animal Science and Zoology

    Cite this

    Mosconi, G., Palermo, F., Carotti, M., Kikuyama, S., Yamamoto, K., & Polzonetti-Magni, A. M. (2006). Neuroendocrine modulation of stress response in the anuran, Rana esculenta. Amphibia Reptilia, 27(3), 401-408. https://doi.org/10.1163/156853806778190141

    Neuroendocrine modulation of stress response in the anuran, Rana esculenta. / Mosconi, Gilberto; Palermo, Francesco; Carotti, Marcello; Kikuyama, Sakae; Yamamoto, Kazutoshi; Polzonetti-Magni, Alberta M.

    In: Amphibia Reptilia, Vol. 27, No. 3, 08.2006, p. 401-408.

    Research output: Contribution to journalArticle

    Mosconi, G, Palermo, F, Carotti, M, Kikuyama, S, Yamamoto, K & Polzonetti-Magni, AM 2006, 'Neuroendocrine modulation of stress response in the anuran, Rana esculenta', Amphibia Reptilia, vol. 27, no. 3, pp. 401-408. https://doi.org/10.1163/156853806778190141
    Mosconi G, Palermo F, Carotti M, Kikuyama S, Yamamoto K, Polzonetti-Magni AM. Neuroendocrine modulation of stress response in the anuran, Rana esculenta. Amphibia Reptilia. 2006 Aug;27(3):401-408. https://doi.org/10.1163/156853806778190141
    Mosconi, Gilberto ; Palermo, Francesco ; Carotti, Marcello ; Kikuyama, Sakae ; Yamamoto, Kazutoshi ; Polzonetti-Magni, Alberta M. / Neuroendocrine modulation of stress response in the anuran, Rana esculenta. In: Amphibia Reptilia. 2006 ; Vol. 27, No. 3. pp. 401-408.
    @article{01201c50f353423da8b580449881cb47,
    title = "Neuroendocrine modulation of stress response in the anuran, Rana esculenta",
    abstract = "In amphibians, as in other vertebrates, stress stimuli have been found to affect different functions, including development, growth, and reproduction. A wide range of responsiveness to stressors has been reported for amphibians; for instance, capture and/or captivity stress induced changes both in the hypothalamus-pituitary-interrenal and hypothalamus-pituitary-gonadal axes. However, few studies have examined the response to stress in terms of recovery and/or adaptation by applying stress paradigms for a short and long-term duration. In the present paper, the short-term captivity stress responses were evaluated in the anuran Rana esculenta by measuring peripheral corticosterone, androgens, prolactin (PRL), and growth hormone (GH) changes. Moreover, in long-term captivity and salinity stress, effects were evaluated by measuring peripheral PRL changes and those of PRL mRNA in the pituitary together with plasma corticosterone and androgens. Short-term (24 h) captivity stress induced an increase of peripheral corticosterone together with that of GH and PRL since these hormones are involved in the {"}alarm phase{"} and in energy demand of stressed animals. The opposite trend was found for peripheral androgens, in view of the negative effects exerted by stress in the reproductive axis. In long-term (1 month) captivity and salinity stress, responses were consistent with the increasing of PRL mRNA at pituitary level, through a long-loop feed-back mechanism depending on the decreasing levels of peripheral PRL, whereas no changes were found in the levels of plasma corticosterone and androgens. Therefore, it seems that Rana esculenta activates different neuroendocrine mechanisms depending on the duration of stress and on the types of stressors.",
    author = "Gilberto Mosconi and Francesco Palermo and Marcello Carotti and Sakae Kikuyama and Kazutoshi Yamamoto and Polzonetti-Magni, {Alberta M.}",
    year = "2006",
    month = "8",
    doi = "10.1163/156853806778190141",
    language = "English",
    volume = "27",
    pages = "401--408",
    journal = "Amphibia - Reptilia",
    issn = "0173-5373",
    publisher = "Brill",
    number = "3",

    }

    TY - JOUR

    T1 - Neuroendocrine modulation of stress response in the anuran, Rana esculenta

    AU - Mosconi, Gilberto

    AU - Palermo, Francesco

    AU - Carotti, Marcello

    AU - Kikuyama, Sakae

    AU - Yamamoto, Kazutoshi

    AU - Polzonetti-Magni, Alberta M.

    PY - 2006/8

    Y1 - 2006/8

    N2 - In amphibians, as in other vertebrates, stress stimuli have been found to affect different functions, including development, growth, and reproduction. A wide range of responsiveness to stressors has been reported for amphibians; for instance, capture and/or captivity stress induced changes both in the hypothalamus-pituitary-interrenal and hypothalamus-pituitary-gonadal axes. However, few studies have examined the response to stress in terms of recovery and/or adaptation by applying stress paradigms for a short and long-term duration. In the present paper, the short-term captivity stress responses were evaluated in the anuran Rana esculenta by measuring peripheral corticosterone, androgens, prolactin (PRL), and growth hormone (GH) changes. Moreover, in long-term captivity and salinity stress, effects were evaluated by measuring peripheral PRL changes and those of PRL mRNA in the pituitary together with plasma corticosterone and androgens. Short-term (24 h) captivity stress induced an increase of peripheral corticosterone together with that of GH and PRL since these hormones are involved in the "alarm phase" and in energy demand of stressed animals. The opposite trend was found for peripheral androgens, in view of the negative effects exerted by stress in the reproductive axis. In long-term (1 month) captivity and salinity stress, responses were consistent with the increasing of PRL mRNA at pituitary level, through a long-loop feed-back mechanism depending on the decreasing levels of peripheral PRL, whereas no changes were found in the levels of plasma corticosterone and androgens. Therefore, it seems that Rana esculenta activates different neuroendocrine mechanisms depending on the duration of stress and on the types of stressors.

    AB - In amphibians, as in other vertebrates, stress stimuli have been found to affect different functions, including development, growth, and reproduction. A wide range of responsiveness to stressors has been reported for amphibians; for instance, capture and/or captivity stress induced changes both in the hypothalamus-pituitary-interrenal and hypothalamus-pituitary-gonadal axes. However, few studies have examined the response to stress in terms of recovery and/or adaptation by applying stress paradigms for a short and long-term duration. In the present paper, the short-term captivity stress responses were evaluated in the anuran Rana esculenta by measuring peripheral corticosterone, androgens, prolactin (PRL), and growth hormone (GH) changes. Moreover, in long-term captivity and salinity stress, effects were evaluated by measuring peripheral PRL changes and those of PRL mRNA in the pituitary together with plasma corticosterone and androgens. Short-term (24 h) captivity stress induced an increase of peripheral corticosterone together with that of GH and PRL since these hormones are involved in the "alarm phase" and in energy demand of stressed animals. The opposite trend was found for peripheral androgens, in view of the negative effects exerted by stress in the reproductive axis. In long-term (1 month) captivity and salinity stress, responses were consistent with the increasing of PRL mRNA at pituitary level, through a long-loop feed-back mechanism depending on the decreasing levels of peripheral PRL, whereas no changes were found in the levels of plasma corticosterone and androgens. Therefore, it seems that Rana esculenta activates different neuroendocrine mechanisms depending on the duration of stress and on the types of stressors.

    UR - http://www.scopus.com/inward/record.url?scp=33748527192&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=33748527192&partnerID=8YFLogxK

    U2 - 10.1163/156853806778190141

    DO - 10.1163/156853806778190141

    M3 - Article

    VL - 27

    SP - 401

    EP - 408

    JO - Amphibia - Reptilia

    JF - Amphibia - Reptilia

    SN - 0173-5373

    IS - 3

    ER -