Neuromagntic responses to chromatic flicker: Implications for photosensitivity

Katsumi Watanabe, Toshiaki Imada, Kenji Nihei, Shinsuke Shimojo

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Excessive cortical excitation due to visual stimulation often leads to photosensitive epilepsy. Here we demonstrate that even in normal subjects, prolonged stimulation with low-luminance chromatic (equiluminant) flicker evokes neuromagnetic activity in the primary visual cortex, which develops slowly (up to 1000ms) and depends on the color combination of flicker. This result suggests that chromatic sensitivity is a critical factor of cortical excitation, which can be amplified over time by a flickering stimulus. We further show that transient activity occurs in the parieto-occipital sulcus as early as 100-400 ms after flicker onset, which is negatively correlated with the later occipital activity. The early parieto-occipital activity may reflect a defensive mechanism that suppresses cortical hyperactivity due to chromatic flicker.

Original languageEnglish
Pages (from-to)2161-2165
Number of pages5
JournalNeuroReport
Volume13
Issue number16
DOIs
Publication statusPublished - 2002 Nov 15
Externally publishedYes

Fingerprint

Color
Reflex Epilepsy
Occipital Lobe
Photic Stimulation
Visual Cortex

Keywords

  • Chromatic flicker
  • Chromatic sensitivity
  • Magnetoencephalography (MEG)
  • Parieto-occipital sulcus
  • Photosensitive epilepsy

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Neuromagntic responses to chromatic flicker : Implications for photosensitivity. / Watanabe, Katsumi; Imada, Toshiaki; Nihei, Kenji; Shimojo, Shinsuke.

In: NeuroReport, Vol. 13, No. 16, 15.11.2002, p. 2161-2165.

Research output: Contribution to journalArticle

Watanabe, Katsumi ; Imada, Toshiaki ; Nihei, Kenji ; Shimojo, Shinsuke. / Neuromagntic responses to chromatic flicker : Implications for photosensitivity. In: NeuroReport. 2002 ; Vol. 13, No. 16. pp. 2161-2165.
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