Neuronal activities in ventrobasal complex of thalamus and in trigeminal main sensory nucleus during EEG desynchronization in anesthetized rats

Kazuyuki Kanosue, Teruo Nakayama, Paul D. Andrew, Zaiwen Shen, Makoto Sato

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Activities of somatosensory relay neurons responding to orofacial mechanical stimulation were examined in the ventrobasal complex of the thalamus (VB) and in the trigeminal main sensory nucleus (MSN) during EEG dysenchronization in urethane-anesthetized rats. EEG desynchronization was induced by scrotal warming in a temperature range of 35-40 °C. Responses of most VB neurons to receptive-field stimulation were augmented during EEG desynchronization, when compared to responses during synchronization. Spontaneous activity of VB neurons also increased with EEG desyncronization. Responses of MSN neurons to receptive-field stimulation did not change appreciably when the EEG pattern was altered. If a VB neuron was induced by iontophoretic application of glutamate to fire at the same rate as seen during EEG desynchronization, a similar increased response to receptive-field stimuli was also observed. The augmented response of the VB neuron during desynchronization may thus have resulted from increased excitability of the neuron itself.

Original languageEnglish
Pages (from-to)90-97
Number of pages8
JournalBrain Research
Volume379
Issue number1
DOIs
Publication statusPublished - 1986 Jul 30
Externally publishedYes

Fingerprint

Ventral Thalamic Nuclei
Thalamus
Electroencephalography
Neurons
Urethane
Sensory Receptor Cells
Glutamic Acid
Temperature

Keywords

  • electroencephalogram (EEG)
  • somatosensory neuron
  • thalamus
  • trigeminal main sensory nucleus

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Neuronal activities in ventrobasal complex of thalamus and in trigeminal main sensory nucleus during EEG desynchronization in anesthetized rats. / Kanosue, Kazuyuki; Nakayama, Teruo; Andrew, Paul D.; Shen, Zaiwen; Sato, Makoto.

In: Brain Research, Vol. 379, No. 1, 30.07.1986, p. 90-97.

Research output: Contribution to journalArticle

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