Nitric oxide suppresses fictive feeding response in Lymnaea stagnalis

Suguru Kobayashi, Hiroto Ogawa, Yutaka Fujito, Etsuro Ito

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Fictive feeding activity was monitored in the buccal ganglia of semi-intact preparations of the pond snail, Lymnaea stagnalis, to examine the effects of nitric oxide (NO) released from motoneurons innervating the esophagus on the feeding response. The present results suggest that first; even the low concentration of constitutive NO precisely regulates the feeding rhythm by suppressing high frequency feeding responses; second, that the high concentration of NO released after activation of the feeding central pattern generator following appetitive stimulation of the lips suppresses the feeding rate, resulting in recurrent inhibition. This is the first direct evidence that NO can function to suppress rhythmic activity in the brain. Copyright (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)209-212
Number of pages4
JournalNeuroscience Letters
Volume285
Issue number3
DOIs
Publication statusPublished - 2000 May 19
Externally publishedYes

Fingerprint

Lymnaea
Nitric Oxide
Central Pattern Generators
Cheek
Snails
Motor Neurons
Feeding Behavior
Lip
Ganglia
Esophagus
Brain

Keywords

  • Central pattern generator
  • Cyclic guanosine monophosphate
  • Feeding
  • Lymnaea
  • Nitric oxide
  • Recurrent inhibition

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Nitric oxide suppresses fictive feeding response in Lymnaea stagnalis. / Kobayashi, Suguru; Ogawa, Hiroto; Fujito, Yutaka; Ito, Etsuro.

In: Neuroscience Letters, Vol. 285, No. 3, 19.05.2000, p. 209-212.

Research output: Contribution to journalArticle

Kobayashi, Suguru ; Ogawa, Hiroto ; Fujito, Yutaka ; Ito, Etsuro. / Nitric oxide suppresses fictive feeding response in Lymnaea stagnalis. In: Neuroscience Letters. 2000 ; Vol. 285, No. 3. pp. 209-212.
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