No effects of short-term vitamin E supplementation on inflammatory and muscle damage markers after repeated bouts of prolonged exercise in healthy young men

Masashi Miyashita, Jong Hoon Park

Research output: Contribution to journalArticle

1 Citation (Scopus)


After a single bout of prolonged strenuous exercise, inflammatory and muscle damage markers increase. The present study investigated whether vitamin E supplementation can attenuate inflammatory (C-reactive protein (CRP) and interleukin-6 (IL-6)) and muscle damage (creatine kinase (CK) and lactate dehydrogenese (LDH)) markers after prolonged repeated bouts of cycling in healthy young men. Eight young males (aged 21-30 y) were received both vitamin E supplement (300 mg/day) and placebo (control) for 14 days separated by at least an interval of 1 month in a randomised, counterbalanced design. On day 12 of both trials, subjects cycled at 80% of maximal heart rate in two, 90-min bouts (150 min rest between each). Blood samples were collected on days 1 (baseline), 12 (pre- and post-exercise 1 and pre- and post-exercise 2), 13, 14, and 15. After 14 days of supplementation, serum α-tocopherol concentrations increased in the vitamin E trial (P

Original languageEnglish
Pages (from-to)383-392
Number of pages10
JournalJapanese Journal of Physical Fitness and Sports Medicine
Issue number3
Publication statusPublished - 2008 Jun
Externally publishedYes



  • Inflammation
  • Muscle damage
  • Repeated exercise
  • Vitamin E

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Physiology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

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