Non-blood contacting electro-hydraulic artificial myocardium (EHAM) improves the myocardial tissue perfusion

Qingtian Wang, Tomoyuki Yambe, Yasuyuki Shiraishi, Xudong Duan, Makoto Yoshizawa, Kouichi Tabayashi, Shinichi Nitta, Mitsuo Umezu

    Research output: Contribution to journalArticle

    7 Citations (Scopus)

    Abstract

    Artificial heart (AH) and ventricular assist devices (VAD) are widely used in the clinical setting to assist severe heart failure patients. The concept of direct cardiac compression (DCC) has been in use for several decades and has advantages over intravascular VAD. The process involves compressing the dysfunctional heart from its epicardial surface to avoid the thromboembolic events and decrease the complications and mortality. An Electro-hydraulic Artificial Myocardium (EHAM) system was designed and fabricated by Tohoku University. This system may assist cardiac contraction and create pulsatile blood flow. The aim of this study was to clearly define the hemodynamic efficiency of the EHAM system in myocardial tissue perfusion during its application in acute animal experiment. Eight healthy adult goats were used; left lateral thoracotomy was performed and the chest was opened by the resection of the 4th and 5th ribs. Hemodynamic parameters including ECG, blood pressure and cardiac output were continuously monitored. Myocardial tissue perfusion was measured by using Omega flow laser fiber attached to the surface of the heart. During the EHAM compression, and increase in blood pressure and myocardial tissue perfusion was observed in all animals when compared with pre-assisted mode. To conclude, EHAM effectively improves myocardial tissue perfusion and increases the pressure on the initiation of direct cardiac compression immediately. Thus it can be a potentially valuable adjunct in the management of severe heart failure.

    Original languageEnglish
    Pages (from-to)229-234
    Number of pages6
    JournalTechnology and Health Care
    Volume13
    Issue number4
    Publication statusPublished - 2005

    Fingerprint

    Heart-Assist Devices
    Myocardium
    Perfusion
    Hydraulics
    Tissue
    Blood pressure
    Hemodynamics
    Animals
    Heart Failure
    Blood Pressure
    Artificial heart
    Artificial Heart
    Pulsatile Flow
    Ribs
    Thoracotomy
    Fiber lasers
    Electrocardiography
    Goats
    Cardiac Output
    Lasers

    ASJC Scopus subject areas

    • Biophysics

    Cite this

    Wang, Q., Yambe, T., Shiraishi, Y., Duan, X., Yoshizawa, M., Tabayashi, K., ... Umezu, M. (2005). Non-blood contacting electro-hydraulic artificial myocardium (EHAM) improves the myocardial tissue perfusion. Technology and Health Care, 13(4), 229-234.

    Non-blood contacting electro-hydraulic artificial myocardium (EHAM) improves the myocardial tissue perfusion. / Wang, Qingtian; Yambe, Tomoyuki; Shiraishi, Yasuyuki; Duan, Xudong; Yoshizawa, Makoto; Tabayashi, Kouichi; Nitta, Shinichi; Umezu, Mitsuo.

    In: Technology and Health Care, Vol. 13, No. 4, 2005, p. 229-234.

    Research output: Contribution to journalArticle

    Wang, Q, Yambe, T, Shiraishi, Y, Duan, X, Yoshizawa, M, Tabayashi, K, Nitta, S & Umezu, M 2005, 'Non-blood contacting electro-hydraulic artificial myocardium (EHAM) improves the myocardial tissue perfusion', Technology and Health Care, vol. 13, no. 4, pp. 229-234.
    Wang Q, Yambe T, Shiraishi Y, Duan X, Yoshizawa M, Tabayashi K et al. Non-blood contacting electro-hydraulic artificial myocardium (EHAM) improves the myocardial tissue perfusion. Technology and Health Care. 2005;13(4):229-234.
    Wang, Qingtian ; Yambe, Tomoyuki ; Shiraishi, Yasuyuki ; Duan, Xudong ; Yoshizawa, Makoto ; Tabayashi, Kouichi ; Nitta, Shinichi ; Umezu, Mitsuo. / Non-blood contacting electro-hydraulic artificial myocardium (EHAM) improves the myocardial tissue perfusion. In: Technology and Health Care. 2005 ; Vol. 13, No. 4. pp. 229-234.
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