Abstract
Purpose was to investigate the linear and nonlinear characteristics of VEPs, and their correlation with the visual parvocellular and magnocellular systems. The VEPs were elicited by pseudorandom luminance modulated stimulation from patients with primary open angle glaucoma and compared with normal subjects. VEPs were recorded from 26 eyes with primary open angle glaucoma (POAG) and 10 eyes of age-matched normal volunteers. To acquire the VEPs, the eye was stimulated with a pseudorandom binary sequence (PRBS) stimulus of 40 sec duration. The first (linear) and second-order (nonlinear) binary kernels were determined by a cross-correlation function between PRBS and VEP. The amplitudes of the first- and second-order kernels decreased with the advancement of POAG. Positive peak latencies around 120 ms of first slice of second-order kernels increased with the advancement of POAG, while the second slice amplitudes were not different in normal, early POAG and moderate POAG patients. These results support the observations in previous studies that the first and second slice response functions reflect the response of the M- and P-pathways, respectively.
| Original language | English |
|---|---|
| Title of host publication | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
| Pages | 4568-4571 |
| Number of pages | 4 |
| DOIs | |
| Publication status | Published - 2006 |
| Event | 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 - New York, NY Duration: 2006 Aug 30 → 2006 Sep 3 |
Other
| Other | 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 |
|---|---|
| City | New York, NY |
| Period | 06/8/30 → 06/9/3 |
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ASJC Scopus subject areas
- Bioengineering
Cite this
Nonlinear characteristics of visual evoked potential in glaucoma patients and their correlation with the visual responses on magnocellular and parvocellular pathways. / Momose, Keiko; Kiyosawa, Motohiro.
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2006. p. 4568-4571 4029341.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Nonlinear characteristics of visual evoked potential in glaucoma patients and their correlation with the visual responses on magnocellular and parvocellular pathways
AU - Momose, Keiko
AU - Kiyosawa, Motohiro
PY - 2006
Y1 - 2006
N2 - Purpose was to investigate the linear and nonlinear characteristics of VEPs, and their correlation with the visual parvocellular and magnocellular systems. The VEPs were elicited by pseudorandom luminance modulated stimulation from patients with primary open angle glaucoma and compared with normal subjects. VEPs were recorded from 26 eyes with primary open angle glaucoma (POAG) and 10 eyes of age-matched normal volunteers. To acquire the VEPs, the eye was stimulated with a pseudorandom binary sequence (PRBS) stimulus of 40 sec duration. The first (linear) and second-order (nonlinear) binary kernels were determined by a cross-correlation function between PRBS and VEP. The amplitudes of the first- and second-order kernels decreased with the advancement of POAG. Positive peak latencies around 120 ms of first slice of second-order kernels increased with the advancement of POAG, while the second slice amplitudes were not different in normal, early POAG and moderate POAG patients. These results support the observations in previous studies that the first and second slice response functions reflect the response of the M- and P-pathways, respectively.
AB - Purpose was to investigate the linear and nonlinear characteristics of VEPs, and their correlation with the visual parvocellular and magnocellular systems. The VEPs were elicited by pseudorandom luminance modulated stimulation from patients with primary open angle glaucoma and compared with normal subjects. VEPs were recorded from 26 eyes with primary open angle glaucoma (POAG) and 10 eyes of age-matched normal volunteers. To acquire the VEPs, the eye was stimulated with a pseudorandom binary sequence (PRBS) stimulus of 40 sec duration. The first (linear) and second-order (nonlinear) binary kernels were determined by a cross-correlation function between PRBS and VEP. The amplitudes of the first- and second-order kernels decreased with the advancement of POAG. Positive peak latencies around 120 ms of first slice of second-order kernels increased with the advancement of POAG, while the second slice amplitudes were not different in normal, early POAG and moderate POAG patients. These results support the observations in previous studies that the first and second slice response functions reflect the response of the M- and P-pathways, respectively.
UR - http://www.scopus.com/inward/record.url?scp=34047161570&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34047161570&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2006.260555
DO - 10.1109/IEMBS.2006.260555
M3 - Conference contribution
C2 - 17945845
AN - SCOPUS:34047161570
SN - 1424400325
SN - 9781424400324
SP - 4568
EP - 4571
BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ER -