Abstract
We propose an in-vitro monitoring device for kinetics and activity of cancer cells in the bone marrow, which can generates a concentration gradient of a gas using hydrophobic-porus microchamber. Pairs of electrodes were used to measure the concentration gradient as the change of electrical resistance of sample solution. The concentration gradient of a gas was successfully measured. When we changed the direction of gas diffusion, we rapidly obtained reverse gradient profile. This concentration gradient can be utilized in biochemical studies including cancer cell monitoring.
| Original language | English |
|---|---|
| Title of host publication | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 |
| Pages | 551-553 |
| Number of pages | 3 |
| Publication status | Published - 2010 Dec 1 |
| Event | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 - Groningen, Netherlands Duration: 2010 Oct 3 → 2010 Oct 7 |
Publication series
| Name | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 |
|---|---|
| Volume | 1 |
Conference
| Conference | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 |
|---|---|
| Country | Netherlands |
| City | Groningen |
| Period | 10/10/3 → 10/10/7 |
Keywords
- Concentration gradient
- Microelectrode
- Neoflon
- Poreflon
ASJC Scopus subject areas
- Control and Systems Engineering
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Cite this
Harada, Y., Kawai, K., & Shoji, S. (2010). On-chip gas concentration gradient formation using poreflon™ and NeoFlon™ for in vitro observation of cancer cell. In 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 (pp. 551-553). (14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010; Vol. 1).