Abstract
We propose an in-vitro monitoring device for kinetics and activity of cancer cells in the bone marrow, which can generates a concentration gradient of a gas using hydrophobic-porus microchamber. Pairs of electrodes were used to measure the concentration gradient as the change of electrical resistance of sample solution. The concentration gradient of a gas was successfully measured. When we changed the direction of gas diffusion, we rapidly obtained reverse gradient profile. This concentration gradient can be utilized in biochemical studies including cancer cell monitoring.
| Original language | English |
|---|---|
| Title of host publication | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 |
| Pages | 551-553 |
| Number of pages | 3 |
| Volume | 1 |
| Publication status | Published - 2010 |
| Event | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 - Groningen Duration: 2010 Oct 3 → 2010 Oct 7 |
Other
| Other | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 |
|---|---|
| City | Groningen |
| Period | 10/10/3 → 10/10/7 |
Fingerprint
Keywords
- Concentration gradient
- Microelectrode
- Neoflon
- Poreflon
ASJC Scopus subject areas
- Control and Systems Engineering
Cite this
On-chip gas concentration gradient formation using poreflon™ and NeoFlon™ for in vitro observation of cancer cell. / Harada, Yu; Kawai, Kentaro; Shoji, Shuichi.
14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. Vol. 1 2010. p. 551-553.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - On-chip gas concentration gradient formation using poreflon™ and NeoFlon™ for in vitro observation of cancer cell
AU - Harada, Yu
AU - Kawai, Kentaro
AU - Shoji, Shuichi
PY - 2010
Y1 - 2010
N2 - We propose an in-vitro monitoring device for kinetics and activity of cancer cells in the bone marrow, which can generates a concentration gradient of a gas using hydrophobic-porus microchamber. Pairs of electrodes were used to measure the concentration gradient as the change of electrical resistance of sample solution. The concentration gradient of a gas was successfully measured. When we changed the direction of gas diffusion, we rapidly obtained reverse gradient profile. This concentration gradient can be utilized in biochemical studies including cancer cell monitoring.
AB - We propose an in-vitro monitoring device for kinetics and activity of cancer cells in the bone marrow, which can generates a concentration gradient of a gas using hydrophobic-porus microchamber. Pairs of electrodes were used to measure the concentration gradient as the change of electrical resistance of sample solution. The concentration gradient of a gas was successfully measured. When we changed the direction of gas diffusion, we rapidly obtained reverse gradient profile. This concentration gradient can be utilized in biochemical studies including cancer cell monitoring.
KW - Concentration gradient
KW - Microelectrode
KW - Neoflon
KW - Poreflon
UR - http://www.scopus.com/inward/record.url?scp=84884332803&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84884332803&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84884332803
SN - 9781618390622
VL - 1
SP - 551
EP - 553
BT - 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
ER -