One-pot synthesis of substituted quinolines by iridium-catalyzed three-component coupling reaction

Takeyuki Igarashi; Takashi Inada; Tadao Sekioka; Takayuki Nakajima; Isao Shimizu

doi:10.1246/cl.2005.106

One-pot synthesis of substituted quinolines by iridium-catalyzed three-component coupling reaction

Takeyuki Igarashi, Takashi Inada, Tadao Sekioka, Takayuki Nakajima, Isao Shimizu^*

^*Corresponding author for this work

Waseda University

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Abstract

A convenient and efficient synthesis of substituted quinolines in a simple one-pot reaction of an arylamine 1, an aromatic aldehyde or aliphatic aldehyde 2 and an aliphatic aldehyde 3 in the presence of transition metal complexes or Lewis acids was developed. Among them, the iridium catalyst [Ir(cod)Cl] ₂ catalyzed the reaction most efficiently.

Original language	English
Pages (from-to)	106-107
Number of pages	2
Journal	Chemistry Letters
Volume	34
Issue number	1
DOIs	https://doi.org/10.1246/cl.2005.106
Publication status	Published - 2005 Jan 5

ASJC Scopus subject areas

Chemistry(all)

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10.1246/cl.2005.106

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abstract = "A convenient and efficient synthesis of substituted quinolines in a simple one-pot reaction of an arylamine 1, an aromatic aldehyde or aliphatic aldehyde 2 and an aliphatic aldehyde 3 in the presence of transition metal complexes or Lewis acids was developed. Among them, the iridium catalyst [Ir(cod)Cl] 2 catalyzed the reaction most efficiently.",

author = "Takeyuki Igarashi and Takashi Inada and Tadao Sekioka and Takayuki Nakajima and Isao Shimizu",

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AU - Igarashi, Takeyuki

AU - Inada, Takashi

AU - Sekioka, Tadao

AU - Nakajima, Takayuki

AU - Shimizu, Isao

PY - 2005/1/5

Y1 - 2005/1/5

N2 - A convenient and efficient synthesis of substituted quinolines in a simple one-pot reaction of an arylamine 1, an aromatic aldehyde or aliphatic aldehyde 2 and an aliphatic aldehyde 3 in the presence of transition metal complexes or Lewis acids was developed. Among them, the iridium catalyst [Ir(cod)Cl] 2 catalyzed the reaction most efficiently.

AB - A convenient and efficient synthesis of substituted quinolines in a simple one-pot reaction of an arylamine 1, an aromatic aldehyde or aliphatic aldehyde 2 and an aliphatic aldehyde 3 in the presence of transition metal complexes or Lewis acids was developed. Among them, the iridium catalyst [Ir(cod)Cl] 2 catalyzed the reaction most efficiently.

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One-pot synthesis of substituted quinolines by iridium-catalyzed three-component coupling reaction

Abstract

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