One-pot synthesis of substituted quinolines by iridium-catalyzed three-component coupling reaction

Takeyuki Igarashi, Takashi Inada, Tadao Sekioka, Takayuki Nakajima, Isao Shimizu

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

A convenient and efficient synthesis of substituted quinolines in a simple one-pot reaction of an arylamine 1, an aromatic aldehyde or aliphatic aldehyde 2 and an aliphatic aldehyde 3 in the presence of transition metal complexes or Lewis acids was developed. Among them, the iridium catalyst [Ir(cod)Cl] 2 catalyzed the reaction most efficiently.

Original languageEnglish
Pages (from-to)106-107
Number of pages2
JournalChemistry Letters
Volume34
Issue number1
DOIs
Publication statusPublished - 2005 Jan 5

ASJC Scopus subject areas

  • Chemistry(all)

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