One-pot synthesis of substituted quinolines by iridium-catalyzed three-component coupling reaction

Takeyuki Igarashi, Takashi Inada, Tadao Sekioka, Takayuki Nakajima, Isao Shimizu

Research output: Contribution to journalArticle

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Abstract

A convenient and efficient synthesis of substituted quinolines in a simple one-pot reaction of an arylamine 1, an aromatic aldehyde or aliphatic aldehyde 2 and an aliphatic aldehyde 3 in the presence of transition metal complexes or Lewis acids was developed. Among them, the iridium catalyst [Ir(cod)Cl] 2 catalyzed the reaction most efficiently.

Original languageEnglish
Pages (from-to)106-107
Number of pages2
JournalChemistry Letters
Volume34
Issue number1
DOIs
Publication statusPublished - 2005 Jan 5

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Quinolines
Iridium
Aldehydes
Lewis Acids
Coordination Complexes
Transition metals
Catalysts

ASJC Scopus subject areas

  • Chemistry(all)

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One-pot synthesis of substituted quinolines by iridium-catalyzed three-component coupling reaction. / Igarashi, Takeyuki; Inada, Takashi; Sekioka, Tadao; Nakajima, Takayuki; Shimizu, Isao.

In: Chemistry Letters, Vol. 34, No. 1, 05.01.2005, p. 106-107.

Research output: Contribution to journalArticle

Igarashi, T, Inada, T, Sekioka, T, Nakajima, T & Shimizu, I 2005, 'One-pot synthesis of substituted quinolines by iridium-catalyzed three-component coupling reaction', Chemistry Letters, vol. 34, no. 1, pp. 106-107. https://doi.org/10.1246/cl.2005.106
Igarashi, Takeyuki ; Inada, Takashi ; Sekioka, Tadao ; Nakajima, Takayuki ; Shimizu, Isao. / One-pot synthesis of substituted quinolines by iridium-catalyzed three-component coupling reaction. In: Chemistry Letters. 2005 ; Vol. 34, No. 1. pp. 106-107.
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