Oxidative C-H/C-H coupling of azine and indole/pyrrole nuclei

Palladium catalysis and synthesis of eudistomin U

Atsushi D. Yamaguchi, Debashis Mandal, Junichiro Yamaguchi, Kenichiro Itami

Research output: Contribution to journalReview article

96 Citations (Scopus)

Abstract

We have developed a palladium-catalyzed C-H/C-H coupling reaction of indoles or pyrroles with azine N-oxides. The reaction proceeds selectively at the C3 position of indoles/pyrroles and the C2 position of azine N-oxides. Furthermore, we have accomplished the synthesis of marine indole alkaloid eudistomin U by utilizing this newly developed C-H/C-H coupling reaction.

Original languageEnglish
Pages (from-to)555-557
Number of pages3
JournalChemistry Letters
Volume40
Issue number6
DOIs
Publication statusPublished - 2011
Externally publishedYes

Fingerprint

Indoles
Pyrroles
Palladium
Oxides
Catalysis
Indole Alkaloids
eudistomin U
indole

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Oxidative C-H/C-H coupling of azine and indole/pyrrole nuclei : Palladium catalysis and synthesis of eudistomin U. / Yamaguchi, Atsushi D.; Mandal, Debashis; Yamaguchi, Junichiro; Itami, Kenichiro.

In: Chemistry Letters, Vol. 40, No. 6, 2011, p. 555-557.

Research output: Contribution to journalReview article

Yamaguchi, Atsushi D. ; Mandal, Debashis ; Yamaguchi, Junichiro ; Itami, Kenichiro. / Oxidative C-H/C-H coupling of azine and indole/pyrrole nuclei : Palladium catalysis and synthesis of eudistomin U. In: Chemistry Letters. 2011 ; Vol. 40, No. 6. pp. 555-557.
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