Abstract
We have developed a palladium-catalyzed C-H/C-H coupling reaction of indoles or pyrroles with azine N-oxides. The reaction proceeds selectively at the C3 position of indoles/pyrroles and the C2 position of azine N-oxides. Furthermore, we have accomplished the synthesis of marine indole alkaloid eudistomin U by utilizing this newly developed C-H/C-H coupling reaction.
| Original language | English |
|---|---|
| Pages (from-to) | 555-557 |
| Number of pages | 3 |
| Journal | Chemistry Letters |
| Volume | 40 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2011 May 27 |
ASJC Scopus subject areas
- Chemistry(all)
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Yamaguchi, A. D., Mandal, D., Yamaguchi, J., & Itami, K. (2011). Oxidative C-H/C-H coupling of azine and indole/pyrrole nuclei: Palladium catalysis and synthesis of eudistomin U. Chemistry Letters, 40(6), 555-557. https://doi.org/10.1246/cl.2011.555