Abstract
We have developed a palladium-catalyzed C-H/C-H coupling reaction of indoles or pyrroles with azine N-oxides. The reaction proceeds selectively at the C3 position of indoles/pyrroles and the C2 position of azine N-oxides. Furthermore, we have accomplished the synthesis of marine indole alkaloid eudistomin U by utilizing this newly developed C-H/C-H coupling reaction.
| Original language | English |
|---|---|
| Pages (from-to) | 555-557 |
| Number of pages | 3 |
| Journal | Chemistry Letters |
| Volume | 40 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2011 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Chemistry(all)
Cite this
Oxidative C-H/C-H coupling of azine and indole/pyrrole nuclei : Palladium catalysis and synthesis of eudistomin U. / Yamaguchi, Atsushi D.; Mandal, Debashis; Yamaguchi, Junichiro; Itami, Kenichiro.
In: Chemistry Letters, Vol. 40, No. 6, 2011, p. 555-557.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Oxidative C-H/C-H coupling of azine and indole/pyrrole nuclei
T2 - Palladium catalysis and synthesis of eudistomin U
AU - Yamaguchi, Atsushi D.
AU - Mandal, Debashis
AU - Yamaguchi, Junichiro
AU - Itami, Kenichiro
PY - 2011
Y1 - 2011
N2 - We have developed a palladium-catalyzed C-H/C-H coupling reaction of indoles or pyrroles with azine N-oxides. The reaction proceeds selectively at the C3 position of indoles/pyrroles and the C2 position of azine N-oxides. Furthermore, we have accomplished the synthesis of marine indole alkaloid eudistomin U by utilizing this newly developed C-H/C-H coupling reaction.
AB - We have developed a palladium-catalyzed C-H/C-H coupling reaction of indoles or pyrroles with azine N-oxides. The reaction proceeds selectively at the C3 position of indoles/pyrroles and the C2 position of azine N-oxides. Furthermore, we have accomplished the synthesis of marine indole alkaloid eudistomin U by utilizing this newly developed C-H/C-H coupling reaction.
UR - http://www.scopus.com/inward/record.url?scp=79956346739&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79956346739&partnerID=8YFLogxK
U2 - 10.1246/cl.2011.555
DO - 10.1246/cl.2011.555
M3 - Review article
AN - SCOPUS:79956346739
VL - 40
SP - 555
EP - 557
JO - Chemistry Letters
JF - Chemistry Letters
SN - 0366-7022
IS - 6
ER -