Oxidative dehydrogenation of dihydropyrimidinones and dihydropyrimidines

Kana Yamamoto*, Ye Grace Chen, Frédéric G. Buono

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

92 Citations (Scopus)


(Chemical Equation Presented) A mild, practical procedure for oxidative dehydrogenation with catalytic amounts of a Cu salt, K2CO 3, and tert-butylhydroperoxide (TBHP) as a terminal oxidant has been developed. This oxidation procedure is generally applicable to dihydropyrimidinones and most dihydropyrimidines.

Original languageEnglish
Pages (from-to)4673-4676
Number of pages4
JournalOrganic Letters
Issue number21
Publication statusPublished - 2005 Oct 13
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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