Oxidative dehydrogenation of dihydropyrimidinones and dihydropyrimidines

Kana Yamamoto; Ye Grace Chen; Frédéric G. Buono

doi:10.1021/ol051879w

Oxidative dehydrogenation of dihydropyrimidinones and dihydropyrimidines

Kana Yamamoto, Ye Grace Chen, Frédéric G. Buono

Global Center for Science and Engineering

Research output: Contribution to journal › Article

79 Citations (Scopus)

Abstract

(Chemical Equation Presented) A mild, practical procedure for oxidative dehydrogenation with catalytic amounts of a Cu salt, K₂CO ₃, and tert-butylhydroperoxide (TBHP) as a terminal oxidant has been developed. This oxidation procedure is generally applicable to dihydropyrimidinones and most dihydropyrimidines.

Original language	English
Pages (from-to)	4673-4676
Number of pages	4
Journal	Organic Letters
Volume	7
Issue number	21
DOIs	https://doi.org/10.1021/ol051879w
Publication status	Published - 2005 Oct 13

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ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

Cite this

Yamamoto, K., Chen, Y. G., & Buono, F. G. (2005). Oxidative dehydrogenation of dihydropyrimidinones and dihydropyrimidines. Organic Letters, 7(21), 4673-4676. https://doi.org/10.1021/ol051879w

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abstract = "(Chemical Equation Presented) A mild, practical procedure for oxidative dehydrogenation with catalytic amounts of a Cu salt, K2CO 3, and tert-butylhydroperoxide (TBHP) as a terminal oxidant has been developed. This oxidation procedure is generally applicable to dihydropyrimidinones and most dihydropyrimidines.",

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Access to Document

10.1021/ol051879w