Oxidative dehydrogenation of dihydropyrimidinones and dihydropyrimidines

Kana Yamamoto, Ye Grace Chen, Frédéric G. Buono

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

(Chemical Equation Presented) A mild, practical procedure for oxidative dehydrogenation with catalytic amounts of a Cu salt, K2CO 3, and tert-butylhydroperoxide (TBHP) as a terminal oxidant has been developed. This oxidation procedure is generally applicable to dihydropyrimidinones and most dihydropyrimidines.

Original languageEnglish
Pages (from-to)4673-4676
Number of pages4
JournalOrganic Letters
Volume7
Issue number21
DOIs
Publication statusPublished - 2005 Oct 13
Externally publishedYes

Fingerprint

tert-Butylhydroperoxide
Dehydrogenation
dehydrogenation
Oxidants
Salts
salts
Oxidation
oxidation

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Oxidative dehydrogenation of dihydropyrimidinones and dihydropyrimidines. / Yamamoto, Kana; Chen, Ye Grace; Buono, Frédéric G.

In: Organic Letters, Vol. 7, No. 21, 13.10.2005, p. 4673-4676.

Research output: Contribution to journalArticle

Yamamoto, Kana ; Chen, Ye Grace ; Buono, Frédéric G. / Oxidative dehydrogenation of dihydropyrimidinones and dihydropyrimidines. In: Organic Letters. 2005 ; Vol. 7, No. 21. pp. 4673-4676.
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