Oxygen binding to β-alkylimidazolyl-meso-tetra(α,α, α,α-o-pivalamidophenyl)porphinatoiron(II) embedded in a phospholipid bilayer under physiological conditions

Kiyoshi Eshima, Makoto Yuasa, Hiroyuki Nishide, Eishun Tsuchida

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

2-Mono(1-{N-[3-(2-methylimidazol-1-yl)propyl]carbamoyl}-2-(N- hexadecylcarbamoyl)ethyl-trans-acrylamido)-5,10,15,20-tetra-(α,α, α,α-o-pivalamidophenyl)porphinatoiron(II) (1a) was synthesized and solubilized in a physiological solution with phospholipid; the oxygen-binding rate constant and affinity were similar to those of erythrocytes in suspension.

Original languageEnglish
Pages (from-to)130-132
Number of pages3
JournalJournal of the Chemical Society, Chemical Communications
Issue number3
Publication statusPublished - 1985

ASJC Scopus subject areas

  • Molecular Medicine

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