Oxygen binding to β-alkylimidazolyl-meso-tetra(α,α, α,α-o-pivalamidophenyl)porphinatoiron(II) embedded in a phospholipid bilayer under physiological conditions

Kiyoshi Eshima, Makoto Yuasa, Hiroyuki Nishide, Eishun Tsuchida

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

2-Mono(1-{N-[3-(2-methylimidazol-1-yl)propyl]carbamoyl}-2-(N- hexadecylcarbamoyl)ethyl-trans-acrylamido)-5,10,15,20-tetra-(α,α, α,α-o-pivalamidophenyl)porphinatoiron(II) (1a) was synthesized and solubilized in a physiological solution with phospholipid; the oxygen-binding rate constant and affinity were similar to those of erythrocytes in suspension.

Original languageEnglish
Pages (from-to)130-132
Number of pages3
JournalJournal of the Chemical Society, Chemical Communications
Issue number3
Publication statusPublished - 1985

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Phospholipids
Rate constants
Suspensions
Erythrocytes
Oxygen
2-methylimidazole

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

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title = "Oxygen binding to β-alkylimidazolyl-meso-tetra(α,α, α,α-o-pivalamidophenyl)porphinatoiron(II) embedded in a phospholipid bilayer under physiological conditions",
abstract = "2-Mono(1-{N-[3-(2-methylimidazol-1-yl)propyl]carbamoyl}-2-(N- hexadecylcarbamoyl)ethyl-trans-acrylamido)-5,10,15,20-tetra-(α,α, α,α-o-pivalamidophenyl)porphinatoiron(II) (1a) was synthesized and solubilized in a physiological solution with phospholipid; the oxygen-binding rate constant and affinity were similar to those of erythrocytes in suspension.",
author = "Kiyoshi Eshima and Makoto Yuasa and Hiroyuki Nishide and Eishun Tsuchida",
year = "1985",
language = "English",
pages = "130--132",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "3",

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TY - JOUR

T1 - Oxygen binding to β-alkylimidazolyl-meso-tetra(α,α, α,α-o-pivalamidophenyl)porphinatoiron(II) embedded in a phospholipid bilayer under physiological conditions

AU - Eshima, Kiyoshi

AU - Yuasa, Makoto

AU - Nishide, Hiroyuki

AU - Tsuchida, Eishun

PY - 1985

Y1 - 1985

N2 - 2-Mono(1-{N-[3-(2-methylimidazol-1-yl)propyl]carbamoyl}-2-(N- hexadecylcarbamoyl)ethyl-trans-acrylamido)-5,10,15,20-tetra-(α,α, α,α-o-pivalamidophenyl)porphinatoiron(II) (1a) was synthesized and solubilized in a physiological solution with phospholipid; the oxygen-binding rate constant and affinity were similar to those of erythrocytes in suspension.

AB - 2-Mono(1-{N-[3-(2-methylimidazol-1-yl)propyl]carbamoyl}-2-(N- hexadecylcarbamoyl)ethyl-trans-acrylamido)-5,10,15,20-tetra-(α,α, α,α-o-pivalamidophenyl)porphinatoiron(II) (1a) was synthesized and solubilized in a physiological solution with phospholipid; the oxygen-binding rate constant and affinity were similar to those of erythrocytes in suspension.

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M3 - Article

SP - 130

EP - 132

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 3

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