5-exo-Selective reductive Mizoroki-Heck reaction of 4-tert-butyl-1-chlorobenzene with 2,5-norbornadiene has been achieved by [PdCl<inf>2</inf>(PCy<inf>3</inf>)<inf>2</inf>]/HCO<inf>2</inf>Na to give 5-exo-(4-tertbutylphenyl)-2-norbornene in 95% yield. When Cs<inf>2</inf>CO<inf>3</inf> is used as a base in the absence of a reducing reagent, an exo-benzocyclobutene-fused norbornene, 6-tert-butyl-1,4,4a,8b-tetrahydro-1,4-methanobiphenylene is produced in 62% yield.
|Number of pages||3|
|Publication status||Published - 2015|
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