Palladium-catalyzed decarbonylative alkynylation of aromatic esters

Toshimasa Okita, Kazushi Kumazawa, Ryosuke Takise, Kei Muto, Kenichiro Itami, Junichiro Yamaguchi

    Research output: Contribution to journalArticle

    31 Citations (Scopus)

    Abstract

    A palladium-catalyzed decarbonylative alkynylation reaction of aromatic esters with terminal alkynes is reported. This reaction allows for halogen-free Sonogashira coupling, resulting in various aryl- and heteroarylalkynes. The utility of the reaction was demonstrated by orthogonal coupling reaction.

    Original languageEnglish
    Pages (from-to)218-220
    Number of pages3
    JournalChemistry Letters
    Volume46
    Issue number2
    DOIs
    Publication statusPublished - 2017

    Fingerprint

    Halogens
    Alkynes
    Palladium
    Esters

    Keywords

    • Alkyne
    • Decarbonylative reaction
    • Palladium

    ASJC Scopus subject areas

    • Chemistry(all)

    Cite this

    Palladium-catalyzed decarbonylative alkynylation of aromatic esters. / Okita, Toshimasa; Kumazawa, Kazushi; Takise, Ryosuke; Muto, Kei; Itami, Kenichiro; Yamaguchi, Junichiro.

    In: Chemistry Letters, Vol. 46, No. 2, 2017, p. 218-220.

    Research output: Contribution to journalArticle

    Okita, Toshimasa ; Kumazawa, Kazushi ; Takise, Ryosuke ; Muto, Kei ; Itami, Kenichiro ; Yamaguchi, Junichiro. / Palladium-catalyzed decarbonylative alkynylation of aromatic esters. In: Chemistry Letters. 2017 ; Vol. 46, No. 2. pp. 218-220.
    @article{9f65d281bc164367bf6d6efa8b7815d6,
    title = "Palladium-catalyzed decarbonylative alkynylation of aromatic esters",
    abstract = "A palladium-catalyzed decarbonylative alkynylation reaction of aromatic esters with terminal alkynes is reported. This reaction allows for halogen-free Sonogashira coupling, resulting in various aryl- and heteroarylalkynes. The utility of the reaction was demonstrated by orthogonal coupling reaction.",
    keywords = "Alkyne, Decarbonylative reaction, Palladium",
    author = "Toshimasa Okita and Kazushi Kumazawa and Ryosuke Takise and Kei Muto and Kenichiro Itami and Junichiro Yamaguchi",
    year = "2017",
    doi = "10.1246/cl.161001",
    language = "English",
    volume = "46",
    pages = "218--220",
    journal = "Chemistry Letters",
    issn = "0366-7022",
    publisher = "Chemical Society of Japan",
    number = "2",

    }

    TY - JOUR

    T1 - Palladium-catalyzed decarbonylative alkynylation of aromatic esters

    AU - Okita, Toshimasa

    AU - Kumazawa, Kazushi

    AU - Takise, Ryosuke

    AU - Muto, Kei

    AU - Itami, Kenichiro

    AU - Yamaguchi, Junichiro

    PY - 2017

    Y1 - 2017

    N2 - A palladium-catalyzed decarbonylative alkynylation reaction of aromatic esters with terminal alkynes is reported. This reaction allows for halogen-free Sonogashira coupling, resulting in various aryl- and heteroarylalkynes. The utility of the reaction was demonstrated by orthogonal coupling reaction.

    AB - A palladium-catalyzed decarbonylative alkynylation reaction of aromatic esters with terminal alkynes is reported. This reaction allows for halogen-free Sonogashira coupling, resulting in various aryl- and heteroarylalkynes. The utility of the reaction was demonstrated by orthogonal coupling reaction.

    KW - Alkyne

    KW - Decarbonylative reaction

    KW - Palladium

    UR - http://www.scopus.com/inward/record.url?scp=85011589288&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=85011589288&partnerID=8YFLogxK

    U2 - 10.1246/cl.161001

    DO - 10.1246/cl.161001

    M3 - Article

    VL - 46

    SP - 218

    EP - 220

    JO - Chemistry Letters

    JF - Chemistry Letters

    SN - 0366-7022

    IS - 2

    ER -