Palladium-catalyzed decarbonylative alkynylation of aromatic esters

Toshimasa Okita, Kazushi Kumazawa, Ryosuke Takise, Kei Muto, Kenichiro Itami, Junichiro Yamaguchi

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    33 Citations (Scopus)

    Abstract

    A palladium-catalyzed decarbonylative alkynylation reaction of aromatic esters with terminal alkynes is reported. This reaction allows for halogen-free Sonogashira coupling, resulting in various aryl- and heteroarylalkynes. The utility of the reaction was demonstrated by orthogonal coupling reaction.

    Original languageEnglish
    Pages (from-to)218-220
    Number of pages3
    JournalChemistry Letters
    Volume46
    Issue number2
    DOIs
    Publication statusPublished - 2017

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    Keywords

    • Alkyne
    • Decarbonylative reaction
    • Palladium

    ASJC Scopus subject areas

    • Chemistry(all)

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