Palladium-catalyzed decarbonylative alkynylation of aromatic esters

Toshimasa Okita, Kazushi Kumazawa, Ryosuke Takise, Kei Muto, Kenichiro Itami, Junichiro Yamaguchi

    Research output: Contribution to journalArticlepeer-review

    38 Citations (Scopus)


    A palladium-catalyzed decarbonylative alkynylation reaction of aromatic esters with terminal alkynes is reported. This reaction allows for halogen-free Sonogashira coupling, resulting in various aryl- and heteroarylalkynes. The utility of the reaction was demonstrated by orthogonal coupling reaction.

    Original languageEnglish
    Pages (from-to)218-220
    Number of pages3
    JournalChemistry Letters
    Issue number2
    Publication statusPublished - 2017


    • Alkyne
    • Decarbonylative reaction
    • Palladium

    ASJC Scopus subject areas

    • Chemistry(all)

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