Palladium-catalyzed decarbonylative alkynylation of aromatic esters

Toshimasa Okita, Kazushi Kumazawa, Ryosuke Takise, Kei Muto, Kenichiro Itami*, Junichiro Yamaguchi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

42 Citations (Scopus)

Abstract

A palladium-catalyzed decarbonylative alkynylation reaction of aromatic esters with terminal alkynes is reported. This reaction allows for halogen-free Sonogashira coupling, resulting in various aryl- and heteroarylalkynes. The utility of the reaction was demonstrated by orthogonal coupling reaction.

Original languageEnglish
Pages (from-to)218-220
Number of pages3
JournalChemistry Letters
Volume46
Issue number2
DOIs
Publication statusPublished - 2017

Keywords

  • Alkyne
  • Decarbonylative reaction
  • Palladium

ASJC Scopus subject areas

  • Chemistry(all)

Fingerprint

Dive into the research topics of 'Palladium-catalyzed decarbonylative alkynylation of aromatic esters'. Together they form a unique fingerprint.

Cite this