Palladium-catalyzed decarbonylative alkynylation of aromatic esters

Toshimasa Okita; Kazushi Kumazawa; Ryosuke Takise; Kei Muto; Kenichiro Itami; Junichiro Yamaguchi

doi:10.1246/cl.161001

Palladium-catalyzed decarbonylative alkynylation of aromatic esters

Toshimasa Okita, Kazushi Kumazawa, Ryosuke Takise, Kei Muto, Kenichiro Itami, Junichiro Yamaguchi

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

A palladium-catalyzed decarbonylative alkynylation reaction of aromatic esters with terminal alkynes is reported. This reaction allows for halogen-free Sonogashira coupling, resulting in various aryl- and heteroarylalkynes. The utility of the reaction was demonstrated by orthogonal coupling reaction.

Original language	English
Pages (from-to)	218-220
Number of pages	3
Journal	Chemistry Letters
Volume	46
Issue number	2
DOIs	https://doi.org/10.1246/cl.161001
Publication status	Published - 2017

Keywords

Alkyne
Decarbonylative reaction
Palladium

ASJC Scopus subject areas

Chemistry(all)

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10.1246/cl.161001

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abstract = "A palladium-catalyzed decarbonylative alkynylation reaction of aromatic esters with terminal alkynes is reported. This reaction allows for halogen-free Sonogashira coupling, resulting in various aryl- and heteroarylalkynes. The utility of the reaction was demonstrated by orthogonal coupling reaction.",

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AU - Okita, Toshimasa

AU - Kumazawa, Kazushi

AU - Takise, Ryosuke

AU - Muto, Kei

AU - Itami, Kenichiro

AU - Yamaguchi, Junichiro

PY - 2017

Y1 - 2017

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KW - Decarbonylative reaction

KW - Palladium

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