Palladium-Catalyzed Decarbonylative Cross-Coupling of Azinecarboxylates with Arylboronic Acids

Kei Muto, Taito Hatakeyama, Kenichiro Itami, Junichiro Yamaguchi

    Research output: Contribution to journalArticlepeer-review

    32 Citations (Scopus)


    The first palladium-catalyzed decarbonylative coupling of phenyl 2-azinecarboxylates and arylboronic acids is presented. The key for the development of this decarbonylative coupling is the use of Pd/dcype as a catalyst. A wide range of 2-azinecarboxylates can undergo the present coupling reaction to afford 2-arylazines. By combination with previously reported nickel-catalyzed decarbonylative coupling, we achieved a chemoselective sequential decarbonylative coupling of pyridine dicarboxylate to synthesize 2,4-diarylpyridine.

    Original languageEnglish
    Pages (from-to)5106-5109
    Number of pages4
    JournalOrganic Letters
    Issue number19
    Publication statusPublished - 2016 Oct 7

    ASJC Scopus subject areas

    • Biochemistry
    • Physical and Theoretical Chemistry
    • Organic Chemistry

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