Palmar fasciitis and polyarthritis associated with gastric carcinoma: Complete resolution after total gastrectomy

Mami Enomoto, Hiroyuki Takemura, Motohiro Suzuki, Takamichi Yuhara, Takao Akama, Kazuhide Yamane, Takayuki Sumida

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Palmar fasciitis and polyarthritis (PFA) is a rare paraneoplastic rheumatic syndrome characterized by flexion contractures of both hands and thickening of palmar fascia. Several reports have suggested that this syndrome is a tumor-associated autoimmune disorder. We report a 44-year-old Japanese man who presented with flexion contractures of both hands associated with thickening of palmar fascia and polyarthritis. These clinical pictures were suggestive of PFA associated with occult neoplasm. Upper gastrointestinal endoscopic examination revealed advanced gastric cancer. Resection of the cancer resulted in a gradual resolution of palmar fasciitis and polyarthritis. This clinical course suggests an underlying tumor-related immunologic process in this syndrome.

Original languageEnglish
Pages (from-to)754-757
Number of pages4
JournalInternal Medicine
Volume39
Issue number9
DOIs
Publication statusPublished - 2000 Sep
Externally publishedYes

Keywords

  • Malignant neoplasm
  • Musculoskeletal manifestation
  • Paraneoplastic syndrome

ASJC Scopus subject areas

  • Internal Medicine

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