Patient-Specific Computational Fluid Mechanics of Cerebral Arteries with Aneurysm and Stent

Kenji Takizawa, Kathleen Schjodt, Anthony Puntel, Nikolay Kostov, Tayfun E. Tezduyar

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

We present patient-specific computational fluid mechanics analysis of blood flow in cerebral arteries with aneurysm and stent. The special arterial fluid mechanics techniques we have developed for this are used in conjunction with the core computational technique, which is the space-time version of the variational multiscale (VMS) method and is called "DST/SST-VMST." The special techniques include using a nonuniform rational basis spline for the spatial representation of the surface over which the stent mesh is built, mesh generation techniques for both the finite- and zero-thickness representations of the stent, techniques for generating refined layers of mesh near the arterial and stent surfaces, and models for representing double stents. We compute the unsteady flow patterns in the aneurysm and investigate how those patterns are influenced by the presence of single and double stents. We also compare the flow patterns obtained with the finite- and zero-thickness representations of the stent. This edition first published 2013

Original languageEnglish
Title of host publicationMultiscale Simulations and Mechanics of Biological Materials
PublisherJohn Wiley and Sons
Pages119-147
Number of pages29
ISBN (Print)9781118350799
DOIs
Publication statusPublished - 2013 Mar 21

Keywords

  • Cardiovascular fluid mechanics
  • Cerebral aneurysms
  • Double stent
  • Mesh generation
  • Patient-specific modeling
  • Stent

ASJC Scopus subject areas

  • Engineering(all)

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    Takizawa, K., Schjodt, K., Puntel, A., Kostov, N., & Tezduyar, T. E. (2013). Patient-Specific Computational Fluid Mechanics of Cerebral Arteries with Aneurysm and Stent. In Multiscale Simulations and Mechanics of Biological Materials (pp. 119-147). John Wiley and Sons. https://doi.org/10.1002/9781118402955.ch7