Patient-specific computer modeling of blood flow in cerebral arteries with aneurysm and stent

Kenji Takizawa, Kathleen Schjodt, Anthony Puntel, Nikolay Kostov, Tayfun E. Tezduyar

Research output: Contribution to journalArticlepeer-review

72 Citations (Scopus)

Abstract

We present the special arterial fluid mechanics techniques we have developed for patient-specific computer modeling of blood flow in cerebral arteries with aneurysm and stent. These techniques are used in conjunction with the core computational technique, which is the space-time version of the variational multiscale (VMS) method and is called "DST/SST-VMST." The special techniques include using NURBS for the spatial representation of the surface over which the stent mesh is built, mesh generation techniques for both the finite- and zero-thickness representations of the stent, techniques for generating refined layers of mesh near the arterial and stent surfaces, and models for representing double stent. We compute the unsteady flow patterns in the aneurysm and investigate how those patterns are influenced by the presence of single and double stents. We also compare the flow patterns obtained with the finite- and zero-thickness representations of the stent.

Original languageEnglish
Pages (from-to)675-686
Number of pages12
JournalComputational Mechanics
Volume50
Issue number6
DOIs
Publication statusPublished - 2013

Keywords

  • Cardiovascular fluid mechanics
  • Cerebral aneurysms
  • Mesh generation
  • Patient-specific modeling
  • Stent

ASJC Scopus subject areas

  • Computational Mechanics
  • Ocean Engineering
  • Mechanical Engineering
  • Computational Theory and Mathematics
  • Computational Mathematics
  • Applied Mathematics

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