Penasulfate A, a new α-glucosidase inhibitor from a marine sponge Penares sp.

Youichi Nakao, Takashi Maki, Shigeki Matsunaga, Rob W M Van Soest, Nobuhiro Fusetani

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

A new α-glucosidase inhibitor, penasulfate A, has been isolated from a marine sponge Penares sp. Its structure was elucidated by spectral and chemical methods to be a scalemic mixture of methyl pipecolates acylated with a novel sulfated fatty acid.

Original languageEnglish
Pages (from-to)1346-1350
Number of pages5
JournalJournal of Natural Products
Volume67
Issue number8
DOIs
Publication statusPublished - 2004 Aug
Externally publishedYes

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Glucosidases
glucosidases
Porifera
Fatty Acids
fatty acids
methodology
penasulfate A

ASJC Scopus subject areas

  • Plant Science
  • Chemistry (miscellaneous)
  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

Cite this

Penasulfate A, a new α-glucosidase inhibitor from a marine sponge Penares sp. / Nakao, Youichi; Maki, Takashi; Matsunaga, Shigeki; Van Soest, Rob W M; Fusetani, Nobuhiro.

In: Journal of Natural Products, Vol. 67, No. 8, 08.2004, p. 1346-1350.

Research output: Contribution to journalArticle

Nakao, Youichi ; Maki, Takashi ; Matsunaga, Shigeki ; Van Soest, Rob W M ; Fusetani, Nobuhiro. / Penasulfate A, a new α-glucosidase inhibitor from a marine sponge Penares sp. In: Journal of Natural Products. 2004 ; Vol. 67, No. 8. pp. 1346-1350.
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