Performance evaluation of continuous blood sampling system for PET study: Comparison of three detector-systems

Keiichi Matsumoto, Masaki Shinoda, Seiichi Yamamoto, Kazumasa Tarutani, Kotaro Minato, Setsu Sakamoto, Michio Senda

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


[Objectives] To measure cerebral blood flow with 15O PET, it is necessary to measure the time course of arterial blood radioactivity. We examined the performance of three different types of continuous blood sampling system. [Methods] Three kinds of continuous blood sampling system were used: a plastic scintillator-based beta detector (conventional beta detector (BETA)), a bismuth germanate (BGO)-based coincidence gamma detector (Pico-count flow-through detector (COINC)) and a Phoswich detector (PD) composed by a combination of plastic scintillator and BGO scintillator. Performance of these systems was evaluated for absolute sensitivity, count rate characteristic, sensitivity to background gamnra photons, and reproducibility for nylon tube geometry. [Results] The absolute sensitivity of the PD was 0.21 cps/Bq for 68Ga positrons at the center of the detector. This was approximately three times higher than BETA, two times higher than COINC. The value measured with BETA was stable, even when background radioactivity was increased. The count rate characteristic of the PD and COINC was linear up to 8 kcps. The reproducibility of sensitivity for nylon tube geometry of COINC was the smallest (C.V. = 1.00%) among the three. PD was the weights the least (3.5 kg) among the three, which is convenient for clinical use. [Conclusions] Each detector has unique characteristics derived from its own structure. Although the performance of all three detectors meets clinical requirement, PD had the highest physical performance.

Original languageEnglish
Pages (from-to)527-534
Number of pages8
JournalKaku igaku. The Japanese journal of nuclear medicine
Issue number4
Publication statusPublished - 2002
Externally publishedYes


  • Beta detector
  • Continuous blood sampling system
  • Phoswich detector
  • Pico-count flow-through detector
  • Positron-emission tomography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Performance evaluation of continuous blood sampling system for PET study: Comparison of three detector-systems'. Together they form a unique fingerprint.

Cite this