Phosphorylated gelatin to enhance cell adhesion to titanium

Shin Hye Park, Liping Zhu, Seiichi Tada, Sei Obuse, Yasuhiro Yoshida, Mariko Nakamura, Tae Il Son, Satoshi Tsuneda, Yoshihiro Ito

    Research output: Contribution to journalArticle

    7 Citations (Scopus)

    Abstract

    Phosphorylated gelatin was prepared for surface modification of titanium to enhance cell attachment. The modified gelatin was synthesized by coupling gelatin with phosphonobutyric acid with water-soluble carbodiimide. Circular dichroism revealed no significant change in the gelatin as a result of phosphorylation. The binding behavior of phosphorylated gelatin on the titanium surface was observed by quartz crystal microbalance. The modified titanium surface was analyzed by measuring the water contact angle. Enhancement of the attachment of osteoblast cells MC-3T3L1 was observed on the phosphorylated-gelatin-modified titanium. Phosphorylation of gelatin was effective for preparation of a cell-adhesive titanium surface.

    Original languageEnglish
    Pages (from-to)1616-1619
    Number of pages4
    JournalPolymer International
    Volume63
    Issue number9
    DOIs
    Publication statusPublished - 2014

    Fingerprint

    Cell adhesion
    Gelatin
    Titanium
    Phosphorylation
    Quartz crystal microbalances
    Osteoblasts
    Dichroism
    Carbodiimides
    Contact angle
    Surface treatment
    Water
    Adhesives
    Acids

    Keywords

    • Cell adhesion
    • Gelatin
    • Phosphorylation
    • Titanium

    ASJC Scopus subject areas

    • Polymers and Plastics

    Cite this

    Park, S. H., Zhu, L., Tada, S., Obuse, S., Yoshida, Y., Nakamura, M., ... Ito, Y. (2014). Phosphorylated gelatin to enhance cell adhesion to titanium. Polymer International, 63(9), 1616-1619. https://doi.org/10.1002/pi.4647

    Phosphorylated gelatin to enhance cell adhesion to titanium. / Park, Shin Hye; Zhu, Liping; Tada, Seiichi; Obuse, Sei; Yoshida, Yasuhiro; Nakamura, Mariko; Son, Tae Il; Tsuneda, Satoshi; Ito, Yoshihiro.

    In: Polymer International, Vol. 63, No. 9, 2014, p. 1616-1619.

    Research output: Contribution to journalArticle

    Park, SH, Zhu, L, Tada, S, Obuse, S, Yoshida, Y, Nakamura, M, Son, TI, Tsuneda, S & Ito, Y 2014, 'Phosphorylated gelatin to enhance cell adhesion to titanium', Polymer International, vol. 63, no. 9, pp. 1616-1619. https://doi.org/10.1002/pi.4647
    Park SH, Zhu L, Tada S, Obuse S, Yoshida Y, Nakamura M et al. Phosphorylated gelatin to enhance cell adhesion to titanium. Polymer International. 2014;63(9):1616-1619. https://doi.org/10.1002/pi.4647
    Park, Shin Hye ; Zhu, Liping ; Tada, Seiichi ; Obuse, Sei ; Yoshida, Yasuhiro ; Nakamura, Mariko ; Son, Tae Il ; Tsuneda, Satoshi ; Ito, Yoshihiro. / Phosphorylated gelatin to enhance cell adhesion to titanium. In: Polymer International. 2014 ; Vol. 63, No. 9. pp. 1616-1619.
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