Photoactivation of cell adhesion on Caged Cell-Culturing Substrates: Effect of terminal functional groups on activation efficiency

Yukiko Kikuchi, Jun Nakanishi, Tohru Takarada, Hidekazu Nakayama, Kazuo Yamaguchi, Yasuhiko Yoshida, Mizuo Maeda

Research output: Contribution to conferencePaper

Abstract

We have recently reported a "Caged Cell-Culturing Substrate", where cell adhesion can be switched on by UV illumination. The substrate is based on an alkylsiloxane terminating with a carboxyl group that is protected by a photocleavable 2-nitrobenzyl group. In the present study, we examined the effect of terminal functional groups on photoactivation of cell adhesion. Among four tested substrates terminating with different functional groups, the photoconversion of cell adhesion was the most effective on that terminating with an amino group.

Original languageEnglish
Number of pages1
Publication statusPublished - 2005 Dec 1
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: 2005 May 252005 May 27

Conference

Conference54th SPSJ Annual Meeting 2005
CountryJapan
CityYokohama
Period05/5/2505/5/27

Keywords

  • Caged compounds
  • Cell adhesion
  • Cell patterning
  • Monolayer
  • Photoswitching

ASJC Scopus subject areas

  • Engineering(all)

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    Kikuchi, Y., Nakanishi, J., Takarada, T., Nakayama, H., Yamaguchi, K., Yoshida, Y., & Maeda, M. (2005). Photoactivation of cell adhesion on Caged Cell-Culturing Substrates: Effect of terminal functional groups on activation efficiency. Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan.