Abstract
Cell migration is a fundamental biological activity, which is involved in both physiological and pathological processes, including embryonic development, inflammation, cancer cell migration, and metastasis. In the present study, we have developed a new method for studying the migration of single cells using a "Caged Cell-Culturing Substrate", which we had recently developed. Cells attached onto a single cell array were released from their geometrical confinements by illumination, which switched on migration of the cells onto the illuminated regions. The formation of cell-adhesive regions can be conducted under fluorescence microscopes. The present method will be useful for studying the regulatory mechanism of cell motility.
| Original language | English |
|---|---|
| Number of pages | 1 |
| Publication status | Published - 2005 Dec 1 |
| Event | 54th SPSJ Annual Meeting 2005 - Yokohama, Japan Duration: 2005 May 25 → 2005 May 27 |
Conference
| Conference | 54th SPSJ Annual Meeting 2005 |
|---|---|
| Country | Japan |
| City | Yokohama |
| Period | 05/5/25 → 05/5/27 |
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Keywords
- Caged compounds
- Cell adhesion
- Cell migration
- Cell patterning
- Monolayer
ASJC Scopus subject areas
- Engineering(all)
Cite this
Nakanishi, J., Takarada, T., Kikuchi, Y., Nakyama, H., Yamaguchi, K., & Maeda, M. (2005). Photonavigation of cell migration on caged cell-culturing substrates. Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan.