Photonavigation of cell migration on caged cell-culturing substrates

Jun Nakanishi, Tohru Takarada, Yukiko Kikuchi, Hidekazu Nakyama, Kazuo Yamaguchi, Mizuo Maeda

Research output: Contribution to conferencePaper

Abstract

Cell migration is a fundamental biological activity, which is involved in both physiological and pathological processes, including embryonic development, inflammation, cancer cell migration, and metastasis. In the present study, we have developed a new method for studying the migration of single cells using a "Caged Cell-Culturing Substrate", which we had recently developed. Cells attached onto a single cell array were released from their geometrical confinements by illumination, which switched on migration of the cells onto the illuminated regions. The formation of cell-adhesive regions can be conducted under fluorescence microscopes. The present method will be useful for studying the regulatory mechanism of cell motility.

Original languageEnglish
Number of pages1
Publication statusPublished - 2005 Dec 1
Externally publishedYes
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: 2005 May 252005 May 27

Conference

Conference54th SPSJ Annual Meeting 2005
CountryJapan
CityYokohama
Period05/5/2505/5/27

Fingerprint

Cells
Substrates
Bioactivity
Adhesives
Microscopes
Lighting
Fluorescence

Keywords

  • Caged compounds
  • Cell adhesion
  • Cell migration
  • Cell patterning
  • Monolayer

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Nakanishi, J., Takarada, T., Kikuchi, Y., Nakyama, H., Yamaguchi, K., & Maeda, M. (2005). Photonavigation of cell migration on caged cell-culturing substrates. Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan.

Photonavigation of cell migration on caged cell-culturing substrates. / Nakanishi, Jun; Takarada, Tohru; Kikuchi, Yukiko; Nakyama, Hidekazu; Yamaguchi, Kazuo; Maeda, Mizuo.

2005. Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan.

Research output: Contribution to conferencePaper

Nakanishi, J, Takarada, T, Kikuchi, Y, Nakyama, H, Yamaguchi, K & Maeda, M 2005, 'Photonavigation of cell migration on caged cell-culturing substrates', Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan, 05/5/25 - 05/5/27.
Nakanishi J, Takarada T, Kikuchi Y, Nakyama H, Yamaguchi K, Maeda M. Photonavigation of cell migration on caged cell-culturing substrates. 2005. Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan.
Nakanishi, Jun ; Takarada, Tohru ; Kikuchi, Yukiko ; Nakyama, Hidekazu ; Yamaguchi, Kazuo ; Maeda, Mizuo. / Photonavigation of cell migration on caged cell-culturing substrates. Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan.1 p.
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