Abstract
An amphiphilic dendritic polymer with polyethylenimine (PEI) as the hydrophilic core, steric ester (STA) as the hydrophobic shell, and azobenzene (AZO) groups as the photoswitchable moieties was synthesized via amidation reaction. The synthesized dendritic macromolecule was characterized by 1H nuclear magnetic resonance (NMR), FT-IR spectroscopy, and dynamic light scattering (DLS). With alternating UV and visible-light irradiation, azobenzene moieties of polyethylenimine-steric ester-azobenzene (PEI-STA-AZO) undergo a reversible isomerization between the cis and trans state. The encapsulation tests demonstrated that PEI-STA-AZO with trans-isomer is not capable of encapsulating anionic guests, whereas the one with cis-isomers is able to encapsulate the anionic guests from the aqueous solution to the organic layer. Molecular modeling by Spartan was utilized to explain the special encapsulation property of PEI-STA-AZO. Azobenzene groups functioned as a reversible "photo-switch" in the dendritic guest-host system, and the reversibility of encapsulation capability of PEI-STA-AZO was also demonstrated. (Figure Presented).
| Original language | English |
|---|---|
| Pages (from-to) | 58-62 |
| Number of pages | 5 |
| Journal | ACS Macro Letters |
| Volume | 4 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2015 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Organic Chemistry
- Polymers and Plastics
- Inorganic Chemistry
- Materials Chemistry
Cite this
Photoswitchable nanocarrier with reversible encapsulation properties. / Cao, Peng Fei; Su, Zhe; De Leon, Al; Advincula, Rigoberto C.
In: ACS Macro Letters, Vol. 4, No. 1, 2015, p. 58-62.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Photoswitchable nanocarrier with reversible encapsulation properties
AU - Cao, Peng Fei
AU - Su, Zhe
AU - De Leon, Al
AU - Advincula, Rigoberto C.
PY - 2015
Y1 - 2015
N2 - An amphiphilic dendritic polymer with polyethylenimine (PEI) as the hydrophilic core, steric ester (STA) as the hydrophobic shell, and azobenzene (AZO) groups as the photoswitchable moieties was synthesized via amidation reaction. The synthesized dendritic macromolecule was characterized by 1H nuclear magnetic resonance (NMR), FT-IR spectroscopy, and dynamic light scattering (DLS). With alternating UV and visible-light irradiation, azobenzene moieties of polyethylenimine-steric ester-azobenzene (PEI-STA-AZO) undergo a reversible isomerization between the cis and trans state. The encapsulation tests demonstrated that PEI-STA-AZO with trans-isomer is not capable of encapsulating anionic guests, whereas the one with cis-isomers is able to encapsulate the anionic guests from the aqueous solution to the organic layer. Molecular modeling by Spartan was utilized to explain the special encapsulation property of PEI-STA-AZO. Azobenzene groups functioned as a reversible "photo-switch" in the dendritic guest-host system, and the reversibility of encapsulation capability of PEI-STA-AZO was also demonstrated. (Figure Presented).
AB - An amphiphilic dendritic polymer with polyethylenimine (PEI) as the hydrophilic core, steric ester (STA) as the hydrophobic shell, and azobenzene (AZO) groups as the photoswitchable moieties was synthesized via amidation reaction. The synthesized dendritic macromolecule was characterized by 1H nuclear magnetic resonance (NMR), FT-IR spectroscopy, and dynamic light scattering (DLS). With alternating UV and visible-light irradiation, azobenzene moieties of polyethylenimine-steric ester-azobenzene (PEI-STA-AZO) undergo a reversible isomerization between the cis and trans state. The encapsulation tests demonstrated that PEI-STA-AZO with trans-isomer is not capable of encapsulating anionic guests, whereas the one with cis-isomers is able to encapsulate the anionic guests from the aqueous solution to the organic layer. Molecular modeling by Spartan was utilized to explain the special encapsulation property of PEI-STA-AZO. Azobenzene groups functioned as a reversible "photo-switch" in the dendritic guest-host system, and the reversibility of encapsulation capability of PEI-STA-AZO was also demonstrated. (Figure Presented).
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UR - http://www.scopus.com/inward/citedby.url?scp=84921324711&partnerID=8YFLogxK
U2 - 10.1021/mz500632r
DO - 10.1021/mz500632r
M3 - Article
AN - SCOPUS:84921324711
VL - 4
SP - 58
EP - 62
JO - ACS Macro Letters
JF - ACS Macro Letters
SN - 2161-1653
IS - 1
ER -