Abstract
Molecularly imprinted polymers (MIP) have become increasingly important in the area of separation and detection. They are emerging tools for the design of structured porous materials having a precise arrangement of functional groups within pores of controlled size and shape. In the present study, covalent molecular imprinting was achieved by using styrene and di-acrylate monomers together with covalently tethered nerve agent (NA) analogs. Due to the nonpersistent nature of this class of nerve agents, the covalent attachment ensures the integrity of the analyte as opposed to a non-covalent approach where the decomposition products of pinacolyl methyl phosphonate (PMP) can lead to a variety of binding cavities based upon the nature of the decomposed products. The binding affinity of the imprinted polymers to the NA analogs, as studied by colorimetric methods, was found to be efficient and highly selective.{A figure is presented}.
| Original language | English |
|---|---|
| Pages (from-to) | 6485-6490 |
| Number of pages | 6 |
| Journal | Polymer |
| Volume | 47 |
| Issue number | 19 |
| DOIs | |
| Publication status | Published - 2006 Sep 7 |
| Externally published | Yes |
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Keywords
- Covalent bonding
- Molecular imprinting
- Pinacolyl methyl phosphonate
ASJC Scopus subject areas
- Polymers and Plastics
- Organic Chemistry
Cite this
Pinacolyl methyl phosphonate (PMP) detection by molecularly imprinted polymers (MIP) : A labile covalent bonding approach. / Taranekar, Prasad; Huang, Chengyu; Advincula, Rigoberto C.
In: Polymer, Vol. 47, No. 19, 07.09.2006, p. 6485-6490.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pinacolyl methyl phosphonate (PMP) detection by molecularly imprinted polymers (MIP)
T2 - A labile covalent bonding approach
AU - Taranekar, Prasad
AU - Huang, Chengyu
AU - Advincula, Rigoberto C.
PY - 2006/9/7
Y1 - 2006/9/7
N2 - Molecularly imprinted polymers (MIP) have become increasingly important in the area of separation and detection. They are emerging tools for the design of structured porous materials having a precise arrangement of functional groups within pores of controlled size and shape. In the present study, covalent molecular imprinting was achieved by using styrene and di-acrylate monomers together with covalently tethered nerve agent (NA) analogs. Due to the nonpersistent nature of this class of nerve agents, the covalent attachment ensures the integrity of the analyte as opposed to a non-covalent approach where the decomposition products of pinacolyl methyl phosphonate (PMP) can lead to a variety of binding cavities based upon the nature of the decomposed products. The binding affinity of the imprinted polymers to the NA analogs, as studied by colorimetric methods, was found to be efficient and highly selective.{A figure is presented}.
AB - Molecularly imprinted polymers (MIP) have become increasingly important in the area of separation and detection. They are emerging tools for the design of structured porous materials having a precise arrangement of functional groups within pores of controlled size and shape. In the present study, covalent molecular imprinting was achieved by using styrene and di-acrylate monomers together with covalently tethered nerve agent (NA) analogs. Due to the nonpersistent nature of this class of nerve agents, the covalent attachment ensures the integrity of the analyte as opposed to a non-covalent approach where the decomposition products of pinacolyl methyl phosphonate (PMP) can lead to a variety of binding cavities based upon the nature of the decomposed products. The binding affinity of the imprinted polymers to the NA analogs, as studied by colorimetric methods, was found to be efficient and highly selective.{A figure is presented}.
KW - Covalent bonding
KW - Molecular imprinting
KW - Pinacolyl methyl phosphonate
UR - http://www.scopus.com/inward/record.url?scp=33747808576&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33747808576&partnerID=8YFLogxK
U2 - 10.1016/j.polymer.2006.07.025
DO - 10.1016/j.polymer.2006.07.025
M3 - Article
VL - 47
SP - 6485
EP - 6490
JO - Polymer (United Kingdom)
JF - Polymer (United Kingdom)
SN - 0032-3861
IS - 19
ER -