Pinnaic acid and tauropinnaic acid: Two novel fatty acids composing a 6-azaspiro[4.5]decane unit from the Okinawan bivalve Pinna muricata

Tong Chou, Makoto Kuramoto, Yuko Otani, Mayumi Shikano, Kazunaga Yazawa, Daisuke Uemura

Research output: Contribution to journalArticle

113 Citations (Scopus)

Abstract

Two novel fatty acids with cPLA2 inhibitory activity, pinnaic acid and tauro-pinnaic acid, were isolated from the Okinawan bivalve Pinna muricata. Their structures, including the relative stereochemistry at C5, C9, C13 and C14, were elucidated by extensive 2D NMR spectroscopic analysis.

Original languageEnglish
Pages (from-to)3871-3874
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number22
DOIs
Publication statusPublished - 1996 May
Externally publishedYes

Fingerprint

Bivalvia
Fatty Acids
Stereochemistry
Acids
Spectroscopic analysis
Nuclear magnetic resonance
decane
pinnaic acid

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Pinnaic acid and tauropinnaic acid : Two novel fatty acids composing a 6-azaspiro[4.5]decane unit from the Okinawan bivalve Pinna muricata. / Chou, Tong; Kuramoto, Makoto; Otani, Yuko; Shikano, Mayumi; Yazawa, Kazunaga; Uemura, Daisuke.

In: Tetrahedron Letters, Vol. 37, No. 22, 05.1996, p. 3871-3874.

Research output: Contribution to journalArticle

Chou, Tong ; Kuramoto, Makoto ; Otani, Yuko ; Shikano, Mayumi ; Yazawa, Kazunaga ; Uemura, Daisuke. / Pinnaic acid and tauropinnaic acid : Two novel fatty acids composing a 6-azaspiro[4.5]decane unit from the Okinawan bivalve Pinna muricata. In: Tetrahedron Letters. 1996 ; Vol. 37, No. 22. pp. 3871-3874.
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