Abstract
Coatings that provide either hydrophobic, hydrophilic, cell adhesive or cell non-adhesive functionalities have been deposited using three-phase low energy plasma-polymerization. The cell adhesive/non-adhesive coatings were tested using E. coli k-12. The four plasma-polymerized coatings are: para-xylene (PX), 1-vinyl-2-pyrrolidinone (VP), polyvinyldifluoride (PVDF) and phosphorous glass (SiPOC), respectively. In addition, micropatterning of PX and VP has been performed on the same silicon substrate. Feature sizes down to 2 μm and precise alignment were obtained using lift-off and cleanroom photolithography techniques. The patterning process used did not influence the wetability of the coatings. The simplicity of the lift-off technique and the sturdiness and versatility of the plasma-polymerized coatings, make this ideal for MEMS, bio-MEMS and microfluidic applications, where patterned surfaces with different functionalities are required on for instance the same microchip.
| Original language | English |
|---|---|
| Pages (from-to) | 390-394 |
| Number of pages | 5 |
| Journal | Sensors and Actuators, A: Physical |
| Volume | 110 |
| Issue number | 1-3 |
| DOIs | |
| Publication status | Published - 2004 Feb 1 |
| Externally published | Yes |
Keywords
- Bioactive surfaces
- Cell adhesive
- Cell non-adhesive
- Lift-off
- Micropatterning
- Plasma-polymerized
ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Mechanical Engineering
- Instrumentation