Plasmonics and templated systems for bioapplications

Brylee David B. Tiu, Rigoberto C. Advincula

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The science of surface plasmons in noble metal nanoparticles and in thin metal film–glass interfaces is driving most innovations in biochemical and biomedical applications. The sensitivity of these charge density oscillations toward changes in the geometry and the surrounding medium is more than capable in detecting antibody–antigen and molecular interactions, diagnosing an array of diseases, and delivering drugs in the form of an absorption peak in the visible to the near-infrared region. Modifications on the physical parameters and functionalities on the surface can be used to control the position of the maximum localized surface plasmon resonance absorbance peak or the minimum bulk SPR reflectivity dip. Several lithographic techniques such as colloidal templating can now produce binary and tertiary patterns with more controlled SPR peaks. On the other hand, the surfaces of plasmonic materials should also be properly functionalized in order to selectively recognize specific analytes. Hence, the flexible low-cost synthesis of artificial antibodies complements the surface plasmon properties of metallic nanomaterials. Continuous progress in these fields should make low-cost and responsive biosensors available for point-of-care applications and personal diagnostics.

Original languageEnglish
Pages (from-to)143-160
Number of pages18
JournalRendiconti Lincei
Volume26
DOIs
Publication statusPublished - 2015 Aug 25
Externally publishedYes

Fingerprint

Point-of-Care Systems
Metal Nanoparticles
Costs and Cost Analysis
Surface Plasmon Resonance
Surface Properties
Nanostructures
Biosensing Techniques
Metals
metals
surface plasmon resonance
nanomaterials
Antibodies
biosensors
nanoparticles
Pharmaceutical Preparations
absorbance
metal
oscillation
complement
cost

Keywords

  • Lithography
  • Molecular imprinting
  • Nanoparticle
  • Plasmon
  • Surface plasmon resonance

ASJC Scopus subject areas

  • Environmental Science(all)
  • Agricultural and Biological Sciences(all)
  • Earth and Planetary Sciences(all)

Cite this

Plasmonics and templated systems for bioapplications. / Tiu, Brylee David B.; Advincula, Rigoberto C.

In: Rendiconti Lincei, Vol. 26, 25.08.2015, p. 143-160.

Research output: Contribution to journalArticle

Tiu, Brylee David B. ; Advincula, Rigoberto C. / Plasmonics and templated systems for bioapplications. In: Rendiconti Lincei. 2015 ; Vol. 26. pp. 143-160.
@article{1dbfd2b3539b4089a2949aae17630160,
title = "Plasmonics and templated systems for bioapplications",
abstract = "The science of surface plasmons in noble metal nanoparticles and in thin metal film–glass interfaces is driving most innovations in biochemical and biomedical applications. The sensitivity of these charge density oscillations toward changes in the geometry and the surrounding medium is more than capable in detecting antibody–antigen and molecular interactions, diagnosing an array of diseases, and delivering drugs in the form of an absorption peak in the visible to the near-infrared region. Modifications on the physical parameters and functionalities on the surface can be used to control the position of the maximum localized surface plasmon resonance absorbance peak or the minimum bulk SPR reflectivity dip. Several lithographic techniques such as colloidal templating can now produce binary and tertiary patterns with more controlled SPR peaks. On the other hand, the surfaces of plasmonic materials should also be properly functionalized in order to selectively recognize specific analytes. Hence, the flexible low-cost synthesis of artificial antibodies complements the surface plasmon properties of metallic nanomaterials. Continuous progress in these fields should make low-cost and responsive biosensors available for point-of-care applications and personal diagnostics.",
keywords = "Lithography, Molecular imprinting, Nanoparticle, Plasmon, Surface plasmon resonance",
author = "Tiu, {Brylee David B.} and Advincula, {Rigoberto C.}",
year = "2015",
month = "8",
day = "25",
doi = "10.1007/s12210-015-0416-3",
language = "English",
volume = "26",
pages = "143--160",
journal = "ATTI Della Accademia Nazionale Dei Lincei Rendiconti Lincei Scienze Fisiche E Naturali",
issn = "1120-6349",
publisher = "Accademia Nazionale dei Lincei",

}

TY - JOUR

T1 - Plasmonics and templated systems for bioapplications

AU - Tiu, Brylee David B.

AU - Advincula, Rigoberto C.

PY - 2015/8/25

Y1 - 2015/8/25

N2 - The science of surface plasmons in noble metal nanoparticles and in thin metal film–glass interfaces is driving most innovations in biochemical and biomedical applications. The sensitivity of these charge density oscillations toward changes in the geometry and the surrounding medium is more than capable in detecting antibody–antigen and molecular interactions, diagnosing an array of diseases, and delivering drugs in the form of an absorption peak in the visible to the near-infrared region. Modifications on the physical parameters and functionalities on the surface can be used to control the position of the maximum localized surface plasmon resonance absorbance peak or the minimum bulk SPR reflectivity dip. Several lithographic techniques such as colloidal templating can now produce binary and tertiary patterns with more controlled SPR peaks. On the other hand, the surfaces of plasmonic materials should also be properly functionalized in order to selectively recognize specific analytes. Hence, the flexible low-cost synthesis of artificial antibodies complements the surface plasmon properties of metallic nanomaterials. Continuous progress in these fields should make low-cost and responsive biosensors available for point-of-care applications and personal diagnostics.

AB - The science of surface plasmons in noble metal nanoparticles and in thin metal film–glass interfaces is driving most innovations in biochemical and biomedical applications. The sensitivity of these charge density oscillations toward changes in the geometry and the surrounding medium is more than capable in detecting antibody–antigen and molecular interactions, diagnosing an array of diseases, and delivering drugs in the form of an absorption peak in the visible to the near-infrared region. Modifications on the physical parameters and functionalities on the surface can be used to control the position of the maximum localized surface plasmon resonance absorbance peak or the minimum bulk SPR reflectivity dip. Several lithographic techniques such as colloidal templating can now produce binary and tertiary patterns with more controlled SPR peaks. On the other hand, the surfaces of plasmonic materials should also be properly functionalized in order to selectively recognize specific analytes. Hence, the flexible low-cost synthesis of artificial antibodies complements the surface plasmon properties of metallic nanomaterials. Continuous progress in these fields should make low-cost and responsive biosensors available for point-of-care applications and personal diagnostics.

KW - Lithography

KW - Molecular imprinting

KW - Nanoparticle

KW - Plasmon

KW - Surface plasmon resonance

UR - http://www.scopus.com/inward/record.url?scp=84938984835&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84938984835&partnerID=8YFLogxK

U2 - 10.1007/s12210-015-0416-3

DO - 10.1007/s12210-015-0416-3

M3 - Article

VL - 26

SP - 143

EP - 160

JO - ATTI Della Accademia Nazionale Dei Lincei Rendiconti Lincei Scienze Fisiche E Naturali

JF - ATTI Della Accademia Nazionale Dei Lincei Rendiconti Lincei Scienze Fisiche E Naturali

SN - 1120-6349

ER -